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1. WO2016018024 - CRYSTALLINE COMPOSITE COMPRISING DAPAGLIFLOZIN AND METHOD FOR PREPARING SAME

Publication Number WO/2016/018024
Publication Date 04.02.2016
International Application No. PCT/KR2015/007821
International Filing Date 27.07.2015
IPC
C07H 15/20 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
15Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
20Carbocyclic rings
A61K 31/70 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
A61P 3/10 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
CPC
A61P 3/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
C07D 309/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
309Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
02having no double bonds between ring members or between ring members and non-ring members
08with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
10Oxygen atoms
Applicants
  • 한미정밀화학주식회사 HANMI FINE CHEMICAL CO., LTD. [KR]/[KR]
Inventors
  • 김기림 KIM, Ki Lim
  • 박철현 PARK, Chulhyun
  • 이재헌 LEE, Jaeheon
  • 장영길 CHANG, Young-kil
Agents
  • 김성호 KIM, Sung Ho
Priority Data
10-2014-009603928.07.2014KR
Publication Language Korean (ko)
Filing Language Korean (KO)
Designated States
Title
(EN) CRYSTALLINE COMPOSITE COMPRISING DAPAGLIFLOZIN AND METHOD FOR PREPARING SAME
(FR) COMPOSITE CRISTALLIN COMPRENANT DE LA DAPAGLIFLOZINE ET SON PROCÉDÉ DE PRÉPARATION
(KO) 다파글리프로진을 포함하는 결정질 복합체 및 이의 제조방법
Abstract
(EN) The present invention relates to a crystalline composite comprising dapagliflozin and a method for preparing the same. More specifically, the present invention provides a novel crystalline composite comprising dapagliflozin, which is an SGLT2 inhibitor, and a preparing method capable of economically preparing the novel crystalline composite at high purity.
(FR) Cette invention concerne un composite cristallin comprenant de la dapagliflozine et son procédé de préparation. Plus spécifiquement, cette invention concerne un nouveau composite cristallin comprenant de la dapagliflozine, qui est un inhibiteur de SGLT2, et un procédé de préparation capable de préparer économiquement ledit nouveau composite cristallin à une pureté élevée.
(KO) 본 발명은 다파글리프로진을 포함하는 결정질 복합체 및 이의 제조방법에 관한 것으로서, 보다 상세하게는 SGLT2 억제제인 다파글리프로진을 포함하는 신규 결정질 복합체 및 상기 신규 결정질 복합체를 경제적으로, 그리고 고순도로 제조할 수 있는 제조방법을 제공한다.
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