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1. WO2016016894 - MEDIA FOR CULTURING PLURIPOTENT STEM CELLS

Publication Number WO/2016/016894
Publication Date 04.02.2016
International Application No. PCT/IL2015/050785
International Filing Date 30.07.2015
IPC
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
073
Embryonic cells or tissues; Foetal cells or tissues
0735
Embryonic stem cells; Embryonic germ cells
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
074
Adult stem cells
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
C12N 5/0735 (2010.01)
C12N 5/074 (2010.01)
C12N 15/00 (2006.01)
CPC
C12N 2500/38
C12N 2500/90
C12N 2501/01
C12N 2501/115
C12N 2501/125
C12N 2501/15
Applicants
  • YEDA RESEARCH AND DEVELOPMENT CO. LTD. [IL/IL]; at the Weizmann Institute of Science P.O. Box 95 7610002 Rehovot, IL
Inventors
  • HANNA, Yaqub; IL
  • NOVERSHTERN, Noa; IL
  • RAIS, Yoach; IL
Agents
  • EHRLICH, Gal; G.E. Ehrlich (1995) Ltd. 11 Menachem Begin Road 5268104 Ramat Gan, IL
Priority Data
62/030,79230.07.2014US
62/167,46928.05.2015US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MEDIA FOR CULTURING PLURIPOTENT STEM CELLS
(FR) MILIEUX POUR LA CULTURE DE CELLULES SOUCHES PLURIPOTENTES
Abstract
(EN)
A culture medium is disclosed which comprises STAT3 activator, an ERK1/2 inhibitor and an Axin stabilizer, and optionally also a PKC inhibitor. Cell cultures comprising same and uses thereof are also disclosed.
(FR)
L'invention concerne un milieu de culture qui comprend un activateur de STAT3, un inhibiteur de ERK 1/2 et un stabilisant de l'axine, et facultativement un inhibiteur de PKC. L'invention concerne également des cultures cellulaires comprenant ceux-ci et des utilisations associées.
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