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1. WO2015189362 - TETRAHYDROTRIAZOLOPYRIMIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES

Publication Number WO/2015/189362
Publication Date 17.12.2015
International Application No. PCT/EP2015/063121
International Filing Date 12.06.2015
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
487
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
C07D 487/04 (2006.01)
A61K 31/519 (2006.01)
A61P 11/00 (2006.01)
A61P 1/00 (2006.01)
CPC
A61K 31/519
A61K 9/0075
A61K 9/008
C07D 487/04
Applicants
  • CHIESI FARMACEUTICI S.P.A. [IT/IT]; Via Palermo, 26/A 43100 Parma, IT
Inventors
  • ARMANI, Elisabetta; IT
  • CAPALDI, Carmelida; IT
  • SUTTON, Jonathan Mark; IT
  • HEALD, Robert Andrew; IT
Agents
  • MINOJA, Fabrizio; IT
Priority Data
14172176.112.06.2014EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) TETRAHYDROTRIAZOLOPYRIMIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES
(FR) DÉRIVÉS DE TÉTRAHYDROTRIAZOLOPYRIMIDINE, COMPOSITIONS PHARMACEUTIQUES LES CONTENANT ET UTILISATIONS
Abstract
(EN)
This invention relates to pyrimidinone derivatives having human neutrophil elastase inhibitory properties, and their use in therapy.
(FR)
L'invention concerne des dérivés de pyrimidinone présentant des propriétés inhibitrices de l'élastase neutrophile humaine, et leur utilisation thérapeutique.
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