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1. WO2015173266 - PEPTIDES AND COMPOSITIONS THEREOF FOR IMPROVEMENT OF GLYCAEMIC MANAGEMENT IN A MAMMAL

Publication Number WO/2015/173266
Publication Date 19.11.2015
International Application No. PCT/EP2015/060522
International Filing Date 12.05.2015
Chapter 2 Demand Filed 11.03.2016
IPC
A61K 38/01 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
01Hydrolysed proteins; Derivatives thereof
C07K 7/08 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
08having 12 to 20 amino acids
C07K 14/47 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 38/018
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
01Hydrolysed proteins; Derivatives thereof
012from animals
018from milk
A61P 1/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
A61P 3/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
A61P 3/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
04Anorexiants; Antiobesity agents
Applicants
  • UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN [IE]/[IE]
  • UNIVERSITY OF LIMERICK [IE]/[IE]
Inventors
  • BRENNAN, Lorraine
  • ROBINSON, Aisling
  • NORONHA, Nessa
  • FITZGERALD, Dick
  • NONGONIERMA, Alice
  • HOLTON, Therese
  • ROCHE, Helen
  • JACQUIER, JC
  • SHIELDS, Denis
  • GIBNEY, Eileen
Agents
  • PURDY, Hugh Barry
Priority Data
14167891.212.05.2014EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) PEPTIDES AND COMPOSITIONS THEREOF FOR IMPROVEMENT OF GLYCAEMIC MANAGEMENT IN A MAMMAL
(FR) PEPTIDES ET COMPOSITIONS COMPRENANT CEUX-CI DESTINÉS À L'AMÉLIORATION DE LA GESTION DE L'INDICE GLYCÉMIQUE CHEZ LE MAMMIFÈRE
Abstract
(EN) A peptide having 12 to 60 amino acids and including (a) a sequence of SEQUENCE ID NO: 11, or (b) a fragment of SEQUENCE ID NO: 11 that includes the sequence of SEQUENCE ID NO: 1 or 5, is described for use in improving glycemic management in a mammal. A composition, for example a food product, that includes substantially all of the peptides of SEQUENCE ID NO:'s 1 to 11, that is capable of reducing post-prandial blood glucose levels, and increasing insulin secretion in humans, is also described.
(FR) L'invention concerne un peptide constitué de 12 à 60 acides aminés et comprenant (a) une séquence de SEQ ID NO : 11, ou (b) un fragment de SEQ ID NO : 11 qui comprend la séquence de SEQ ID NO : 1 ou 5, ce peptide étant destiné à être utilisé pour améliorer la gestion de la glycémie chez le mammifère. L'invention concerne également une composition, par exemple un produit alimentaire, qui comprend sensiblement toutes les peptides de séquences de SEQ ID NO : 1 à 11, pouvant diminuer la glycémie post-prandiale et d'augmenter la sécrétion d'insuline chez l'homme.
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