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1. WO2015171003 - PROCESS FOR OBTAINING OPTICALLY ACTIVE PIRLINDOLE ENANTIOMERS AND SALTS THEREOF

Publication Number WO/2015/171003
Publication Date 12.11.2015
International Application No. PCT/PT2014/000027
International Filing Date 09.05.2014
IPC
C07B 57/00 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
57Separation of optically-active organic compounds
C07D 487/06 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
06Peri-condensed systems
CPC
A61K 31/495
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
C07B 2200/07
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
2200Indexing scheme relating to specific properties of organic compounds
07Optical isomers
C07B 57/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
57Separation of optically-active compounds
C07D 487/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
C07D 487/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
02in which the condensed system contains two hetero rings
06Peri-condensed systems
Applicants
  • TECNIMEDE SOCIEDADE TECNICO-MEDICINAL S.A. [PT]/[PT]
Inventors
  • PARDAL FILIPE, Augusto Eugénio
  • EUFRÁSIO PEDROSO, Pedro Filipe
  • ALMEIDA PECORELLI, Susana Marques
  • CASIMIRO CAIXADO, Carlos Alberto Eufrásio
  • LOPES, Ana Sofia da Conceição
  • DAMIL, João Carlos Ramos
  • E OLIVEIRA SANTOS, Pedro Paulo de Lacerda
Agents
  • FERREIRA PINTO, Francisca
Priority Data
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) PROCESS FOR OBTAINING OPTICALLY ACTIVE PIRLINDOLE ENANTIOMERS AND SALTS THEREOF
(FR) PROCÉDÉ D'OBTENTION D'ÉNANTIOMÈRES DE PIRLINDOLE OPTIQUEMENT ACTIFS ET DE SELS DE CEUX-CI
Abstract
(EN) The present invention provides a new process for obtaining optically active pirlindole enantiomers, in the form of a free base or in the form of pharmaceutically acceptable salts. The products obtained according to the present invention are enantiomerically pure and are useful in medicine.
(FR) La présente invention concerne un nouveau procédé d'obtention d'énantiomères de pirlindole optiquement actifs, sous forme d'une base libre ou sous forme de sels pharmaceutiquement acceptables. Les produits obtenus selon la présente invention sont énantiomériquement purs et sont utiles en médecine.
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