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1. (WO2015170247) LIPOSOMES CONTAINING DI-HOMO-GAMMA LINOLENIC ACID (DGLA), FORMULATIONS CONTAINING THEM AND USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2015/170247 International Application No.: PCT/IB2015/053267
Publication Date: 12.11.2015 International Filing Date: 05.05.2015
Chapter 2 Demand Filed: 04.03.2016
IPC:
A61K 9/00 (2006.01) ,A61K 9/127 (2006.01) ,A61K 31/202 (2006.01) ,A61K 31/353 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
127
Liposomes
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
20
having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
202
having three or more double bonds, e.g. linolenic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
35
having six-membered rings with one oxygen as the only ring hetero atom
352
condensed with carbocyclic rings, e.g. cannabinols, methantheline
353
3,4-Dihydrobenzopyrans, e.g. chroman, catechin
Applicants:
FIDIA FARMACEUTICI S.P.A. [IT/IT]; Via Ponte della Fabbrica 3/A I-35031 Abano Terme PD, IT
Inventors:
BROTZU, Giovanni; IT
BROTZU, Giuseppe; IT
Agent:
ASENSIO, Raffaella; IT
PERANI, Aurelio; IT
ACCO, Stefania; IT
BONVICINI, Davide; IT
CICERI, Fabio; IT
SGOBBA, Marco; IT
Priority Data:
CA2014A00000306.05.2014IT
Title (EN) LIPOSOMES CONTAINING DI-HOMO-GAMMA LINOLENIC ACID (DGLA), FORMULATIONS CONTAINING THEM AND USE THEREOF
(FR) LIPOSOMES CONTENANT UN ACIDE LINOLÉNIQUE DI-HOMO-GAMMA (DGLA), FORMULATIONS LES CONTENANT, ET LEUR UTILISATION
Abstract:
(EN) Phospholipid liposomes comprising at least one polyunsaturated fatty acid selected in the group consisting of dihomo-gamma-linolenic acid (DGLA), linoleic acid, gamma-linolenic acid, arachidonic acid, docosatetraenoic acid, a plant estrogen selected from equol, genistein, daidzein, glycitein; a compound able to increase cation capacity of the liposome selected from essential amino acids, carnitine and derivatives thereof; a stabilizer selected from cholesterol, cholesterol sulphate and stearylamine, for use in the treatment of alopecia, baldness, hair loss, and related pharmaceutical compositions containing them as active ingredients in association with suitable excipients and/or diluents.
(FR) L'invention concerne des liposomes phospholipidiques comprenant au moins un acide gras polyinsaturé choisi dans le groupe constitué par l'acide linolénique gamma dihomo (DGLA), l'acide linoléique, l'acide linolénique gamma, l'acidea rachidonique, l'acide docosatetraénoïque, et un œstrogène végétal choisi parmi l'équol, la génistéine, la daidzéine, et la glycitéine ; un composé pouvant augmenter la capacité de cations du liposome choisi parmi des acides aminés essentiels, la carnitine et des dérivés de ceux-ci ; un stabilisateur choisi parmi le cholestérol, le sulfate de cholestérol et la stéarylamine, pour utilisation dans le traitement d'alopécie, de calvitie, de perte de cheveux, et des compositions pharmaceutiques associées les contenant comme principes actifs en association avec des excipients et/ou diluants appropriés.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: Italian (IT)