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1. (WO2015161301) DEVICE AND METHODS OF USING DEVICE FOR DETECTION OF AMINOACIDOPATHIES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2015/161301 International Application No.: PCT/US2015/026546
Publication Date: 22.10.2015 International Filing Date: 17.04.2015
IPC:
C12P 19/34 (2006.01) ,C12Q 1/68 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19
Preparation of compounds containing saccharide radicals
26
Preparation of nitrogen-containing carbohydrates
28
N-glycosides
30
Nucleotides
34
Polynucleotides, e.g. nucleic acids, oligoribonucleotides
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
UNIVERSITY OF MARYLAND, COLLEGE PARK [US/US]; 2130 Mitchell Building College Park, Maryland 20742, US
CHILDREN'S NATIONAL MEDICAL CENTER [US/US]; 111 Michigan Avenue, NW Washington, District of Columbia 20010, US
Inventors:
AYYUB, Omar Bilal; US
HELIGMAN, Brian Theodore; US
KOFINAS, Peter; US
SUMMAR, Marshall Lynn; US
CABRERA-LUQUE, Juan Manuel; US
CUNNINGHAM, Gary; US
Agent:
ZURAWSKI, John A.; US
Priority Data:
61/981,12617.04.2014US
62/112,01904.02.2015US
Title (EN) DEVICE AND METHODS OF USING DEVICE FOR DETECTION OF AMINOACIDOPATHIES
(FR) DISPOSITIF ET PROCÉDÉS D'UTILISATION DU DISPOSITIF POUR LA DÉTECTION D'AMINOACIDOPATHIES
Abstract:
(EN) The present disclosure relates to a biosensor capable of measuring the total concentration of one or a plurality of amino acids with the use of a reaction surface comprising one or a plurality of metabolic enzymes or functional fragments thereof, but wherein the reaction surface does not comprise an electrode or electrically conductive support. In some embodiments, the biosensor comprises use of a thermophilic bacterial metabolic enzyme immobilized or attached to the reaction surface.
(FR) La présente invention concerne un bio-capteur pouvant mesurer la concentration totale d'un ou de plusieurs acides aminés au moyen d'une surface de réaction comportant une ou plusieurs enzymes métaboliques ou des fragments fonctionnels de celles-ci, mais dans lequel la surface de réaction ne comprend pas d'électrode ni de support conducteur de l'électricité. Dans certains modes de réalisation, le bio-capteur comprend l'utilisation d'une enzyme métabolique de bactérie thermophile, immobilisée ou fixée à la surface de réaction.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP3132049JP2017513487US20170198329