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1. WO2015143223 - METHODS AND MATERIALS FOR TREATING CANCER

Publication Number WO/2015/143223
Publication Date 24.09.2015
International Application No. PCT/US2015/021576
International Filing Date 19.03.2015
IPC
A61K 39/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
CPC
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
A61K 2039/5256
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
51comprising whole cells, viruses or DNA/RNA
525Virus
5256expressing foreign proteins
A61K 2039/53
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
51comprising whole cells, viruses or DNA/RNA
53DNA (RNA) vaccination
A61K 2039/54
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
54characterised by the route of administration
A61K 2039/552
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
55characterised by the host/recipient, e.g. newborn with maternal antibodies
552Veterinary vaccine
A61K 2039/55516
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
555characterised by a specific combination antigen/adjuvant
55511Organic adjuvants
55516Proteins; Peptides
Applicants
  • MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH [US]/[US]
  • UNIVERSITY OF LEEDS [GB]/[GB]
Inventors
  • VILE, Richard G.
  • KOTTKE, Timothy J.
  • THOMPSON, Jill M.
  • PULIDO, Jose S.
  • MELCHER, Alan A.
  • SELBY, Peter
Agents
  • FINN III, J. Patrick
Priority Data
61/955,67719.03.2014US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND MATERIALS FOR TREATING CANCER
(FR) PROCÉDÉS ET MATÉRIEL POUR TRAITER LE CANCER
Abstract
(EN) This document provides methods and materials for treating cancer. For example, methods and materials for identifying antigens and combinations of antigens that can be used to treat cancer as well as combinations of antigens having the ability to reduce established tumors (e.g., gliomas) within a mammal (e.g., a human) are provided. In general, one aspect of this document features a composition comprising, or consisting essentially of, nucleic acid encoding HIF-2a, SOX-10, C-MYC, and TYRP-1, wherein the composition comprises less than 100 separate nucleic acid molecules.
(FR) La présente invention concerne des procédés et du matériel pour traiter le cancer. Cette invention concerne par exemple des méthodes et du matériel permettant d'identifier des antigènes et des associations d'antigènes qui peuvent être utilisés pour traiter le cancer, ainsi que des associations d'antigènes capables de réduire les tumeurs établies (par exemple les gliomes) chez un mammifère (par exemple chez l'homme). En général, un aspect de la présente invention concerne une composition comprenant de l'acide nucléique codant HIF-2a, SOX-10, C-MYC et TYRP-1, ou étant essentiellement constituée dudit acide nucléique, ladite composition contenant moins de 100 molécules d'acide nucléique séparées.
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