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1. WO2015142305 - MONOCLONAL ANTIBODIES DEVELOPED AGAINST H-FABP AND THE USE THEREOF

Publication Number WO/2015/142305
Publication Date 24.09.2015
International Application No. PCT/TR2015/000115
International Filing Date 19.03.2015
IPC
C07K 16/18 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
G01N 33/577 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
577involving monoclonal antibodies
CPC
C07K 16/18
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
G01N 2333/47
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2333Assays involving biological materials from specific organisms or of a specific nature
435from animals; from humans
46from vertebrates
47Assays involving proteins of known structure or function as defined in the subgroups
G01N 2800/324
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
32Cardiovascular disorders
324Coronary artery diseases, e.g. angina pectoris, myocardial infarction
G01N 33/566
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
566using specific carrier or receptor proteins as ligand binding reagents ; where possible specific carrier or receptor proteins are classified with their target compounds
Applicants
  • S.K TEKNOLOJI ARASTIRMA GELISTIRME SAN. VE TIC. LTD. STI. [TR]/[TR]
Inventors
  • OZEN, Mehmet Ozgun
  • GURHAN, Saime Ismet
Agents
  • YALCINER, Ugur G. (YALCINER PATENT & CONSULTING LTD.)
Priority Data
2014/0325820.03.2014TR
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) MONOCLONAL ANTIBODIES DEVELOPED AGAINST H-FABP AND THE USE THEREOF
(FR) ANTICORPS MONOCLONAUX DÉVELOPPÉS CONTRE H-FABP ET LEUR UTILISATION
Abstract
(EN) With this invention, monoclonal antibodies that has affinity to heart-type fatty acid binding protein (h-FABP) have been determined. Monoclonal antibodies were developed against the h-FABP protein. The said monoclonal antibodies can be used in determining h-FABP levels in blood, serum or plasma of an individual in immunological and serological tests. As a result, this immune test kit may be used in the diagnosis of the heart attack and/or in the detection of therapeutics which have toxicity towards cardiac muscles.
(FR) Cette invention concerne des anticorps monoclonaux présentant une affinité pour la protéine cardiaque de liaison aux acides gras (h-FABP, heart-type fatty acid binding protein). Des anticorps monoclonaux ont été développés contre la protéine h-FABP. Lesdits anticorps monoclonaux peuvent être utilisés dans la détermination des teneurs en h-FABP dans le sang, le sérum ou le plasma d'un individu dans des tests immunologiques et sérologiques. Par conséquent, ce kit de test immunitaire peut être utilisé dans le diagnostic de la crise cardiaque et/ou dans la détection d'agents thérapeutiques qui présentent une toxicité pour les muscles cardiaques.
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