Feedback
Settings

Settings

Goto Application

1. WO2015134839 - P-SUBSTITUTED ASYMMETRIC UREAS AND MEDICAL USES THEREOF

PermaLink
Publication Number WO/2015/134839
Publication Date 11.09.2015
International Application No. PCT/US2015/019112
International Filing Date 06.03.2015
IPC
C07D 401/06 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
06linked by a carbon chain containing only aliphatic carbon atoms
C07C 275/06 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
275Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups
04having nitrogen atoms of urea groups bound to acyclic carbon atoms
06of an acyclic and saturated carbon skeleton
C07C 275/26 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
275Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups
26having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
C07D 401/12 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
C07D 211/58 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
211Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
04with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
06having no double bonds between ring members or between ring members and non-ring members
36with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
56Nitrogen atoms
58attached in position 4
C07D 211/60 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
211Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
04with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
06having no double bonds between ring members or between ring members and non-ring members
36with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
CPC
A61P 1/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
A61P 1/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
04for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A61P 1/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
08for nausea, cinetosis or vertigo; Antiemetics
A61P 1/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
10Laxatives
A61P 1/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
A61P 1/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Applicants
  • HELSINN HEALTHCARE SA [CH]/[CH]
  • GIULIANO, Claudio [IT]/[IT] (US)
  • GARCIA RUBIO, Silvina [US]/[US] (US)
  • DAINA, Antoine [CH]/[CH] (US)
  • GUAINAZZI, Angelo [CH]/[US] (US)
  • PIETRA, Claudio [IT]/[IT] (US)
Inventors
  • GIULIANO, Claudio
  • GARCIA RUBIO, Silvina
  • DAINA, Antoine
  • GUAINAZZI, Angelo
  • PIETRA, Claudio
Agents
  • SULLIVAN, Clark, G.
Priority Data
61/949,66407.03.2014US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) P-SUBSTITUTED ASYMMETRIC UREAS AND MEDICAL USES THEREOF
(FR) URÉES ASYMÉTRIQUES P-SUBSTITUÉES ET UTILISATIONS MÉDICALES DE CELLES-CI
front page image
Abstract
(EN)
Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general Formula (I): or pharmaceutically acceptable salts thereof.
(FR)
La présente invention concerne des composés, des compositions et des méthodes pour la prévention et/ou le traitement de maladies qui sont médiées de façon pathophysiologique par le récepteur de ghréline. Les composés ont la Formule générale (I), il peut aussi s'agir des sels pharmaceutiquement acceptables de ceux-ci.
Also published as
AU2015227011
CA2931836
CL2016-2267
CL2016002267
CN106170485
CONC2016/0002770
CR20160458
CRCR2016-000458
DK3114118
DOP2016000161
EA201691796
ECSP201665157
EP3114118
GE14255
GE14255/1
GEP20186908B
GT201600176
ID2017/10423
IL246844
IN201627033568
JP2017507116
JP2020011996
KR1020160130218
MDa 2016 0100
MX2016011535
MYPI 2016702679
NI201600091
PE2016-1414
PH1/2016/501483
PT3114118
SG11201603924Y
TH171895
TN2016000177
UAa201610056
VN1201603753
VN50375
Latest bibliographic data on file with the International Bureau
# -