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1. (WO2015134599) PLATINUM(IV) COMPOUNDS AND METHODS OF MAKING AND USING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2015/134599 International Application No.: PCT/US2015/018720
Publication Date: 11.09.2015 International Filing Date: 04.03.2015
IPC:
A61K 31/282 (2006.01) ,C07D 225/08 (2006.01) ,C07D 249/16 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
28
Compounds containing heavy metals
282
Platinum compounds
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
225
Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
04
condensed with carbocyclic rings or ring systems
08
condensed with two six-membered rings
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
249
Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
16
condensed with carbocyclic rings or ring systems
Applicants:
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. [US/US]; Boyd Graduate Studies Research Center Athens, GA 30602-7411, US
Inventors:
DHAR, Shanta; US
PATHAK, Rakesh, K.; US
POPIK, Vladimir, V.; US
MCNITT, Christopher, D.; US
Agent:
ALBIN, Loren, D.; US
Priority Data:
61/947,70304.03.2014US
61/976,55908.04.2014US
PCT/US2014/06999712.12.2014US
Title (EN) PLATINUM(IV) COMPOUNDS AND METHODS OF MAKING AND USING SAME
(FR) COMPOSÉS DE PLATINE(IV) ET PROCÉDÉS DE PREPARATION ET D'UTILISATION DE CEUX-CI
Abstract:
(EN) Reactions of 1,3-dipole-functional (e.g., azide-functional) platinum(IV) compounds with cyclic alkynes under conditions effective for a cycloaddition reaction to form a heterocyclic compound are disclosed herein. In certain embodiments, the conditions effective for the cycloaddition reaction to form the heterocyclic compound includes the substantial absence of added catalyst (e.g., copper catalyst).
(FR) La présente invention se rapporte à des réactions de composés de platine(IV) 1,3-dipôle-fonctionnel (par exemple, azide-fonctionnel) avec des alcynes cycliques dans des conditions efficaces pour une réaction de cycloaddition afin de former un composé hétérocyclique. Dans certains modes de réalisation, les conditions efficaces pour la réaction de cycloaddition afin de former le composé hétérocyclique comprennent l'absence substantielle de catalyseur ajouté (par exemple, un catalyseur à base de cuivre).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)