Processing

Please wait...

Settings

Settings

Goto Application

1. WO2015131848 - MTOR-INDEPENDENT ACTIVATOR OF TFEB FOR AUTOPHAGY ENHANCEMENT AND USES THEREOF

Publication Number WO/2015/131848
Publication Date 11.09.2015
International Application No. PCT/CN2015/073764
International Filing Date 06.03.2015
IPC
A61K 31/12 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
12Ketones
CPC
A61K 31/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
12Ketones
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 25/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
14for treating abnormal movements, e.g. chorea, dyskinesia
16Anti-Parkinson drugs
A61P 25/28
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
28for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applicants
  • HONG KONG BAPTIST UNIVERSITY [CN]/[CN]
Inventors
  • LI, Min
  • SONG, Juxian
  • ZENG, Yu
  • LIU, Liangfeng
Agents
  • CHINA PAT INTELLECTUAL PROPERTY OFFICE
Priority Data
14/609,43830.01.2015US
61/949,23306.03.2014US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) MTOR-INDEPENDENT ACTIVATOR OF TFEB FOR AUTOPHAGY ENHANCEMENT AND USES THEREOF
(FR) ACTIVATEUR DU GÈNE TFEB INDÉPENDANT DE MTOR POUR L'AMÉLIORATION DE L'AUTOPHAGIE ET UTILISATIONS ASSOCIÉES
Abstract
(EN) A composition comprising an autophagy enhancement compound is disclosed. Small molecules that are able to enhance autophagy and lysosome biogenesis by activating the gene TFEB which can prevent the accumulation of toxic protein aggregates in treating neurodegenerative diseases are disclosed.
(FR) La présente invention concerne une composition comprenant un composé améliorant l'autophagie. L'invention concerne de petites molécules qui permettent d'améliorer l'autophagie et la biogenèse des lysosomes par activation du gène TFEB pouvant empêcher l'accumulation d'agrégats de protéines toxiques, lors du traitement de maladies neurodégénératives.
Related patent documents
Latest bibliographic data on file with the International Bureau