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1. WO2015131073 - TRIAZOLE-BASED READER MOLECULES AND METHODS FOR SYNTHESIZING AND USE THEREOF

Publication Number WO/2015/131073
Publication Date 03.09.2015
International Application No. PCT/US2015/018062
International Filing Date 27.02.2015
IPC
G01N 27/327 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
26by investigating electrochemical variables; by using electrolysis or electrophoresis
28Electrolytic cell components
30Electrodes, e.g. test electrodes; Half-cells
327Biochemical electrodes
CPC
C07C 319/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
319Preparation of thiols, sulfides, hydropolysulfides or polysulfides
02of thiols
12by reactions not involving the formation of mercapto groups
C07D 249/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
249Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
02not condensed with other rings
081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
10with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
G01N 27/3276
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
26by investigating electrochemical variables; by using electrolysis or electrophoresis
28Electrolytic cell components
30Electrodes, e.g. test electrodes; Half-cells
327Biochemical electrodes ; , e.g. electrical or mechanical details for in vitro measurements
3275Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
3276being a hybridisation with immobilised receptors
Applicants
  • ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY [US]/[US]
Inventors
  • ZHANG, Peiming
  • LINDSAY, Stuart
  • BISWAS, Sovan
  • SEN, Suman
Agents
  • HOPKINS, Brian P.
Priority Data
61/945,65927.02.2014US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) TRIAZOLE-BASED READER MOLECULES AND METHODS FOR SYNTHESIZING AND USE THEREOF
(FR) MOLÉCULES DE LECTURE À BASE DE TRIAZOLE ET PROCÉDÉS POUR LEUR SYNTHÈSE ET LEUR UTILISATION
Abstract
(EN) Triazole-based molecules, methods of making and using the same are provided. Triazole-based molecules may be used as reading molecules and incorporated into or operatively-linked with electrodes, for example, and used in recognition tunneling systems to identify individual and/or sequences of molecules (e.g., DNA bases, carbohydrates, proteins, peptides, and/or amino-acids).
(FR) L'invention porte sur des molécules à base de triazole, et sur des procédés de préparation et d'utilisation de celles-ci. Les molécules à base de triazole peuvent être utilisées comme molécules de lecture et incorporées dans des électrodes ou fonctionnellement reliées à des électrodes, par exemple, et être utilisées dans des systèmes de tunnelisation de reconnaissance pour identifier des molécules individuelles et/ou des séquences de molécules (par exemple, des bases d'ADN, des glucides, des protéines, des peptides, et/ou des acides aminés).
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