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1. (WO2015128875) A PROCESS FOR PREPARATION OF DABIGATRAN ETEXILATE MESYLATE AND INTERMEDIATES THEREOF
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2015/128875 International Application No.: PCT/IN2015/000100
Publication Date: 03.09.2015 International Filing Date: 23.02.2015
IPC:
C07D 401/12 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
401
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02
containing two hetero rings
12
linked by a chain containing hetero atoms as chain links
Applicants:
MEGAFINE PHARMA (P) LTD. [IN/IN]; Sethna, 4th Floor 55, Maharishi Karve Road, Marine Lines Mumbai 400002, IN
Inventors:
MATHAD, Vijayavitthal Thippannachar; IN
SOLANKI, Pavankumar Vrajlal; IN
UPPELLI, Sekhar Babu; IN
SARODE, Ganesh Gitaram; IN
Agent:
MAYUR DHAYGUDE; Intellectual Property Management Megafine Pharma (P9 Ltd., Plot No. 31 to 35 & 48 to 51/201 Lkhmapur, Tal. Dindori Dist. Nashik 422202 Maharashtra, IN
Priority Data:
675/MUM/201426.02.2014IN
Title (EN) A PROCESS FOR PREPARATION OF DABIGATRAN ETEXILATE MESYLATE AND INTERMEDIATES THEREOF
(FR) PROCÉDÉ DE PRÉPARATION DE DABIGATRAN ÉTÉXILATE MÉSYLATE ET DE SES INTERMÉDIAIRES
Abstract:
(EN) The present invention relates to an improved process for the preparation of Dabigatran etexilate and its acid addition salts thereof, wherein the said process substantially eliminates the potential impurities. The present invention also relates to an intermediate of Dabigatran etexilate and process for preparation thereof.
(FR) La présente invention concerne un procédé amélioré pour préparer du dabigatran étéxilate et ses sels d'addition d'acide, ledit procédé permettant d'éliminer sensiblement les éventuelles impuretés. La présente invention concerne également un intermédiaire du dabigatran étéxilate et son procédé de préparation.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)