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1. (WO2015127302) SELECTIVE MATRIX METALLOPROTEINASE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2015/127302 International Application No.: PCT/US2015/016950
Publication Date: 27.08.2015 International Filing Date: 20.02.2015
IPC:
C07D 331/02 (2006.01)
Applicants: UNIVERSITY OF NOTRE DAME DU LAC[US/US]; Office Of Technology Transfer 940 Grace Hall Notre Dame, Indiana 46556, US
Inventors: CHANG, Mayland; US
MOBASHERY, Shahriar; US
Agent: HAUKAAS, Michael H.; US
Priority Data:
61/942,51620.02.2014US
62/088,38005.12.2014US
Title (EN) SELECTIVE MATRIX METALLOPROTEINASE INHIBITORS
(FR) INHIBITEURS SÉLECTIFS DE MÉTALLOPROTÉINASES MATRICIELLES
Abstract: front page image
(EN) The invention provides compounds, compositions, and methods for the treatment of diseases, disorders, or conditions that are modulated by matrix metalloproteinases (MMPs). The compounds can be selective MMP inhibitors, for example, selective inhibitors of MMP-2, MMP-9, and/or MMP-14. The disease, disorder, or condition can include, for example, stroke, neurological disorders, ophthalmological disorders, or wounds, such as chronic wounds or diabetic wounds.
(FR) L'invention concerne des composés, des compositions et des procédés destinés au traitement de maladies, de troubles ou d'états qui sont modulés par les métalloprotéinases matricielles (MMP). Les composés peuvent être des inhibiteurs sélectifs de MMP, par exemple, des inhibiteurs sélectifs de la MMP-2, de la MMP-9 et/ou de la MMP-14. La maladie, le trouble ou l'état peut comprendre, par exemple, un accident vasculaire cérébral, des troubles neurologiques, des troubles ophtalmologiques ou des blessures, telles que les blessures chroniques ou les lésions diabétiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)