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1. (WO2015127242) DE NOVO DESIGN OF ALLOSTERIC PROTEINS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/127242    International Application No.:    PCT/US2015/016868
Publication Date: 27.08.2015 International Filing Date: 20.02.2015
IPC:
C12P 21/08 (2006.01), C12N 15/10 (2006.01), C40B 50/06 (2006.01)
Applicants: PRESIDENT AND FELLOWS OF HARVARD COLLEGE [US/US]; 17 Quincy Street Cambridge, Massachusetts 02138 (US)
Inventors: CHURCH, George M.; (US).
RAMAN, Srivatsan; (US).
TAYLOR, Noah D.; (US)
Agent: IWANICKI, John P.; (US)
Priority Data:
61/942,755 21.02.2014 US
Title (EN) DE NOVO DESIGN OF ALLOSTERIC PROTEINS
(FR) CONCEPTION DE NOVO DE PROTÉINES ALLOSTÉRIQUES
Abstract: front page image
(EN)Methods and compositions for making and isolating allosteric DNA binding proteins that bind to one or more allosteric effectors to induce a conformation change in the proteins are provided.
(FR)La présente invention concerne des procédés et des compositions permettant de produire et d'isoler des protéines de liaison allostériques d'ADN qui se lient à un ou plusieurs effecteurs allostériques pour induire un changement dans la conformation de la protéine.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)