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1. (WO2015127201) HIV-2 NUCLEIC ACIDS AND METHODS OF DETECTION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2015/127201 International Application No.: PCT/US2015/016814
Publication Date: 27.08.2015 International Filing Date: 20.02.2015
IPC:
C07K 14/16 (2006.01) ,C12Q 1/70 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005
from viruses
08
RNA viruses
15
Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
155
Lentiviridae, e.g. human immunodeficiency virus (HIV), visna-maedi virus, equine infectious anaemia virus
16
HIV-1
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
70
involving virus or bacteriophage
Applicants:
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES [US/US]; National Institutes Of Health Office Of Technology Transfer 6011 Executive Blvd., Suite 325 MSC 7660 Bethesda, MD 20892-7660, US
Inventors:
CURTIS, Kelly, A.; US
YOUNGPAIROJ, Ae, S.; US
OWEN, Sherry, M.; US
PAU, Chou-pong; US
GRANADE, Timothy, C.; US
NIEDZWIEDZ, Philip; US
RUDOLPH, Donna, L.; US
Agent:
GRAF, Susan, W.; US
Priority Data:
61/943,00121.02.2014US
Title (EN) HIV-2 NUCLEIC ACIDS AND METHODS OF DETECTION
(FR) ACIDES NUCLÉIQUES DU VIH-2 ET LEURS PROCÉDÉS DE DÉTECTION
Abstract:
(EN) Disclosed herein are methods of detecting HIV-2 nucleic acids in a sample (such as from a sample infected with or suspected to be infected with HIV-2). In some examples, the methods include LAMP or RT-LAMP, while in other examples, the methods include hybridization of a probe to an HIV-2 nucleic acid, including, but not limited to real-time PCR. Sets of LAMP primers for detection of HIV-2 Group A and Group B nucleic acids are provided herein. Sets of probes and primers for real-time PCR detection of HIV-2 nucleic acids are also provided herein. Finally, primers for amplification of HIV-2 nucleic acids are provided. Also disclosed are isolated HIV-2 nucleic acids, vectors including the HIV-2 nucleic acids, and cells transformed with vectors including HIV-2 nucleic acids.
(FR) L'invention concerne des procédés de détection d'acides nucléiques du VIH-2 dans un échantillon (par exemple un échantillon infecté par le VIH-2 ou suspecté de l'être). Dans certains exemples, lesdits procédés comprennent une amplification LAMP ou RT-LAMP, tandis que, dans d'autres exemples, les procédés impliquent l'hybridation d'une sonde à un acide nucléique du VIH-2, pouvant intervenir, par exemple, mais la liste n'est pas limitative, dans le cadre d'une PCR en temps réel. L'invention concerne également des ensembles d'amorces pour amplification LAMP permettant la détection des acides nucléiques des groupes A et B du VIH-2. L'invention concerne, en outre, des ensembles de sondes et d'amorces pour la détection par PCR en temps réel d'acides nucléiques du VIH-2. Enfin, l'invention concerne des amorces pour l'amplification d'acides nucléiques du VIH-2. L'invention concerne encore des acides nucléiques isolés du VIH-2, des vecteurs comportant des acides nucléiques du VIH-2, et des cellules transformées au moyen de vecteurs comportant des acides nucléiques du VIH-2.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)