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1. (WO2015127163) PYRIDOXAMINE FOR THE TREATMENT OF SICKLE CELL DISEASE, THALASSEMIA AND RELATED BLOOD DISEASES

Pub. No.:    WO/2015/127163    International Application No.:    PCT/US2015/016753
Publication Date: Fri Aug 28 01:59:59 CEST 2015 International Filing Date: Sat Feb 21 00:59:59 CET 2015
IPC: A61K 31/44
A61P 3/10
A61P 7/06
A61P 13/12
Applicants: NANOMETICS LLC
ALBERT EINSTEIN COLLEGE OF MEDICINE, INC.
Inventors: ISAACMAN, Steven
ACHARYA, Seetharama, A.
Title: PYRIDOXAMINE FOR THE TREATMENT OF SICKLE CELL DISEASE, THALASSEMIA AND RELATED BLOOD DISEASES
Abstract:
The present invention relates to treatments and therapies for anemia conditions and diseases of the blood, and more particular is a therapy for the acute and chronic treatment of sickle cell diseases and thalassemia by administration of pyridoxamine, or a pharmaceutically acceptable salt thereof, optionally in combination with an additional bioactive agent.