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1. (WO2015126816) COMBINATION THERAPY FOR HEMATOLOGICAL MALIGNANCIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/126816    International Application No.:    PCT/US2015/016128
Publication Date: 27.08.2015 International Filing Date: 17.02.2015
IPC:
A61K 38/15 (2006.01), A61K 45/06 (2006.01), A61K 31/4184 (2006.01), A61P 35/00 (2006.01)
Applicants: CELGENE CORPORATION [US/US]; 86 Morris Avenue Summit, NJ 07901 (US)
Inventors: CARNITI, Cristiana; (IT).
GIMONDI, Silvia; (IT).
VENDRAMIN, Antonio; (IT).
CORRADINI, Paolo; (IT)
Agent: RIEGER, Dale, L.; (US)
Priority Data:
61/941,364 18.02.2014 US
Title (EN) COMBINATION THERAPY FOR HEMATOLOGICAL MALIGNANCIES
(FR) POLYTHÉRAPIE POUR TUMEURS MALIGNES HÉMATOLOGIQUES
Abstract: front page image
(EN)Methods of treating, preventing or managing T-cell lymphomas are disclosed. The methods encompass administration of an HDAC inhibitor romidepsin and an alkylating agent bendamustine, also known as TREANDA®. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods provided herein are also disclosed
(FR)L'invention concerne des méthodes de traitement, de prévention ou de gestion de lymphomes à lymphocytes T. Les méthodes comprennent l'administration d'un inhibiteur de HDAC, tel que la romidepsine, et d'un agent d'alkylation, tel que la bendamustine, qu'on connait également sous le nom de TREANDA ®. L'invention concerne également des compositions pharmaceutiques et des formes posologiques individuelles appropriées pour l'utilisation dans les méthodes de la présente invention.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)