WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2015126434) METHODS FOR ACUTE AND LONG-TERM TREATMENT OF DRUG ADDICTION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/126434    International Application No.:    PCT/US2014/019692
Publication Date: 27.08.2015 International Filing Date: 28.02.2014
Chapter 2 Demand Filed:    18.12.2015    
IPC:
A61K 31/55 (2006.01), A61P 25/04 (2006.01), A61P 25/30 (2006.01)
Applicants: DEMERX, INC. [US/US]; 305 South Andrews Avenue, Suite 515 Fort Lauderdale, Florida 33301 (US)
Inventors: FRIEDHOFF, Lawrence; (US)
Agent: MORLEY, Marc T.; (US)
Priority Data:
61/941,387 18.02.2014 US
61/945,746 27.02.2014 US
Title (EN) METHODS FOR ACUTE AND LONG-TERM TREATMENT OF DRUG ADDICTION
(FR) MÉTHODES DE TRAITEMENT AIGU ET À LONG TERME DE LA TOXICOMANIE
Abstract: front page image
(EN)This invention is directed to a method of treating opioid or opioid-like drug addiction, including acute and post-acute withdrawal symptoms, comprising treating an addicted patient with noribogaine at a dosage that provides an average serum concentration of about 50 ng/mL to about 850 ng/mL (AUC/24 h) under conditions where the QT interval prolongation does not exceed about 50 milliseconds.
(FR)L'invention concerne une méthode de traitement de la pharmacodépendance aux substances opioïdes ou de type opioïde, y compris des symptômes de sevrage aigu et post-aigu, comprenant le traitement d'un patient toxicomane par la noribogaïne à un dosage qui permet une concentration sérique moyenne d'environ 50 ng/mL à environ 850 ng/mL (AUC/24h) dans des conditions où le prolongement d'intervalle QT ne dépasse pas environ 50 millisecondes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)