WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2015126192) PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING SENSORINEURAL HEARING LOSS, CONTAINING CYSTEINYL LEUKOTRIENE RECEPTOR ANTAGONIST AND GINKGO LEAF EXTRACT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/126192    International Application No.:    PCT/KR2015/001693
Publication Date: 27.08.2015 International Filing Date: 23.02.2015
IPC:
A61K 31/47 (2006.01), A61P 27/16 (2006.01)
Applicants: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION [KR/KR]; (Woncheon-dong) 206, World cup-ro, Yeongtong-gu, Suwon-si Gyeonggi-do 443-749 (KR)
Inventors: PARK, Sang Myun; (KR).
PARK, Jung Sub; (KR).
CHOUNG, Yun Hoon; (KR).
KIM, Yeon Ju; (KR)
Agent: KIM, Soon Woong; (KR)
Priority Data:
10-2014-0019665 20.02.2014 KR
Title (EN) PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING SENSORINEURAL HEARING LOSS, CONTAINING CYSTEINYL LEUKOTRIENE RECEPTOR ANTAGONIST AND GINKGO LEAF EXTRACT
(FR) COMPOSITION PHARMACEUTIQUE POUR TRAITER OU PRÉVENIR UNE PERTE D'AUDITION NEUROSENSORIELLE, CONTENANT UN ANTAGONISTE DE RÉCEPTEUR DE CYSTÉINYL-LEUCOTRIÈNE ET UN EXTRAIT DE FEUILLE DE GINKGO
(KO) 시스테인 류코트리엔 수용체 길항제 및 은행잎 추출물을 포함하는 감각신경성 난청의 치료 또는 예방용 약학 조성물
Abstract: front page image
(EN)The present invention provides a compound having an effect of preventing and/or treating the damage or degeneration of cochlear (and vestibular) mother cells and spiral ganglion neurons by downregulating a cysteinyl leukotriene receptor. Particularly, the present invention provides a composition for preventing or treating sensorineural hearing loss, containing a cysteinyl leukotriene receptor and a ginkgo leaf extract as active ingredients, on the basis of the co-administration of a cysteinyl leukotriene receptor and a ginkgo leaf extract having an excellent effect of protecting hearing.
(FR)La présente invention concerne un composé ayant un effet de prévention et/ou traitement de lésion ou dégénérescence de cellules mères cochléaires (et vestibulaires) et de neurones de ganglions spiraux, en provoquant une régulation négative d'un récepteur de cystéinyl-leucotriène. En particulier, la présente invention concerne une composition pour prévenir ou traiter une perte d'audition neurosensorielle, contenant un récepteur de cystéinyl-leucotriène et un extrait de feuille de ginkgo comme principes actifs, sur la base de l'administration simultanée d'un récepteur de cystéinyl-leucotriène et d'un extrait de feuille de ginkgo ayant un excellent effet de protection auditive.
(KO)본 발명은 시스테인 류코트리엔 수용체(cysteinyl leukotriene receptor)를 다운 조절함으로써 와우(및 전정) 모세포 및 나선 신경절 신경원의 손상이나 변성을 예방 및/또는 치료하는 효과를 갖는 화합물을 제공한다. 특히, 본 발명은 시스테인 류코트리엔 수용체(cysteinyl leukotriene receptor)과 더불어 은행잎 추출물의 병용투여가 청력 보호효과가 뛰어남을 바탕으로, 시스테인 류코트리엔 수용체(cysteinyl leukotriene receptor) 및 은행잎 추출물을 유효성분으로 포함하는 감각신경성 난청의 예방 또는 치료용 조성물을 제공한다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)