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1. (WO2015125969) TRANSDERMAL PREPARATION COMPRISING TRIPTAN-TYPE MEDICINE

Pub. No.:    WO/2015/125969    International Application No.:    PCT/JP2015/055223
Publication Date: Fri Aug 28 01:59:59 CEST 2015 International Filing Date: Wed Feb 25 00:59:59 CET 2015
IPC: A61K 31/404
A61K 9/08
A61K 31/4045
A61K 31/4196
A61K 31/422
A61K 31/454
A61K 47/10
A61K 47/18
A61K 47/24
A61K 47/34
A61P 25/06
Applicants: MEDRX CO., LTD.
株式会社メドレックス
Inventors: YAMASAKI, Keiko
山崎 啓子
Title: TRANSDERMAL PREPARATION COMPRISING TRIPTAN-TYPE MEDICINE
Abstract:
The present invention provides: a transdermal liquid preparation which comprises a triptan-type medicine; and a liquid-type adhesive skin patch which is produced by impregnating a resin porous sheet with the transdermal liquid preparation. The transdermal liquid preparation according to the present invention contains a triptan-type medicine or a salt thereof, phosphatidylcholine and propylene glycol, and does not contain a hydrophobic solvent. It is preferred that the transdermal liquid preparation according to the present invention additionally contains an alkanolamine. Examples of the triptan-type medicine include sumatriptan, zolmitriptan, eletriptan, rizatriptan and naratriptan. As the alkanol amine, triethanolamine can be used preferably.