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1. (WO2015125934) ENHANCER OF ANTI-TUMOR EFFECT OF ANTI-CANCER AGENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/125934    International Application No.:    PCT/JP2015/054843
Publication Date: 27.08.2015 International Filing Date: 20.02.2015
IPC:
A61K 33/06 (2006.01), A61K 31/282 (2006.01), A61K 31/337 (2006.01), A61K 31/513 (2006.01), A61K 31/704 (2006.01), A61P 35/00 (2006.01)
Applicants: YAMAMOTO, Hirofumi [JP/JP]; (JP).
MORI, Masaki [JP/JP]; (JP)
Inventors: YAMAMOTO, Hirofumi; (JP).
MORI, Masaki; (JP).
DOKI, Yuichiro; (JP).
WU, Xin; (JP)
Agent: YAMADA, Iichiro; (JP)
Priority Data:
2014-031060 20.02.2014 JP
Title (EN) ENHANCER OF ANTI-TUMOR EFFECT OF ANTI-CANCER AGENT
(FR) AMPLIFICATEUR DE L'EFFET ANTITUMORAL D'UN AGENT ANTICANCÉREUX
(JA) 抗癌剤の抗腫瘍効果の増強剤
Abstract: front page image
(EN)The purpose of the present invention is to provide an enhancer which can cause the efficient accumulation of an anti-cancer agent in a tumor tissue to enhance the anti-tumor effect of an anti-cancer agent. When carbonate apatite is administered in combination with an anti-cancer agent, the anti-cancer agent can be accumulated in a tumor tissue with high efficiency and therefore the anti-tumor effect of the anti-cancer agent can be enhanced dramatically.
(FR)La présente invention vise à fournir un amplificateur qui puisse provoquer l'accumulation efficace d'un agent anticancéreux dans un tissu tumoral dans le but d'amplifier l'effet antitumoral d'un agent anticancéreux. Quand du carbonate-apatite est administré en association avec un agent anticancéreux, l'agent anticancéreux peut s'accumuler dans un tissu tumoral avec un rendement élevé, de sorte que l'effet antitumoral de l'agent anticancéreux peut être considérablement amplifié.
(JA) 本発明の目的は、抗癌剤を腫瘍組織に効率的に集積させることにより抗腫瘍効果 を増強させる増強剤を提供することである。 抗癌剤と共に、炭酸アパタイトを投与することによって、抗癌剤を腫瘍組織に効率的に集積させることができ、抗癌剤の抗腫瘍効果が劇的に増強される。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)