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1. (WO2015125098) BIOMARKERS FOR LUNG CANCER, ASSOCIATED METHODS, AND KITS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/125098    International Application No.:    PCT/IB2015/051262
Publication Date: 27.08.2015 International Filing Date: 19.02.2015
IPC:
G01N 33/574 (2006.01)
Applicants: IMMUNEPHARMA S.R.L. [IT/IT]; Via Giovanni Paolo II, 132 I-84084 Fisciano (SA) (IT)
Inventors: PINTO, Aldo; (IT).
AQUINO, Rita Patrizia; (IT).
SORRENTINO, Rosalinda; (IT).
TERLIZZI, Michela; (IT)
Agent: DI GIOVINE, Paolo; (IT)
Priority Data:
RM2014A000080 24.02.2014 IT
Title (EN) BIOMARKERS FOR LUNG CANCER, ASSOCIATED METHODS, AND KITS
(FR) BIOMARQUEURS DU CANCER DU POUMON ET LEURS PROCÉDÉS ET LEUR KIT DE DIAGNOSTIC
Abstract: front page image
(EN)The present invention relates to the use as a biomarker of the active form of a human caspase protein, preferably the human caspase-4 or caspase-1, or of the active form of the protein encoded by an orthologue gene of the human caspase protein, preferably by an orthologue gene of the human caspase-4, for example the murine caspase-11 protein, in a method of diagnosis and/or prognosis and/or of monitoring the progression of a tumor, particularly lung cancer.
(FR)La présente invention concerne l'utilisation, en tant que biomarqueur, de la forme active d'une protéine de caspase humaine, de préférence la caspase-4 ou la caspase-1 humaine, ou de la forme active de la protéine codée par un gène orthologue de la protéine de caspase humaine, de préférence par un gène orthologue de la caspase-4 humaine, par exemple la protéine caspase-11 murine, dans un procédé de diagnostic et/ou de pronostic et/ou de surveillance de la progression d'une tumeur, en particulier du cancer du poumon.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: Italian (IT)