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1. (WO2015124064) THIOPHENE AS HEPATITIS C VIRUS INHIBITOR OR VARIANT DERIVATIVE THEREOF AND USE THEREOF FOR DRUG PREPARATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/124064    International Application No.:    PCT/CN2015/072375
Publication Date: 27.08.2015 International Filing Date: 06.02.2015
IPC:
C07D 409/14 (2006.01), C07D 413/14 (2006.01), C07D 491/113 (2006.01), C07D 495/04 (2006.01), C07D 401/14 (2006.01), A61K 31/4178 (2006.01), A61K 31/422 (2006.01), A61K 31/4439 (2006.01), A61P 31/14 (2006.01)
Applicants: CHANGZHOU YINSHENG PHARMACEUTICAL CO., LTD. [CN/CN]; Weitang Chemical Zone, Xinbei District Changzhou, Jiangsu 213033 (CN).
SICHUAN UNIVERSITY [CN/CN]; No.24, South Section 1, First Ring Road, Wuhou District Chengdu, Sichuan 610065 (CN)
Inventors: CHEN, Shuhui; (CN).
ZHU, Wenyuan; (CN).
WANG, Jianfei; (CN).
LI, Jian; (CN).
WEI, Yuquan; (CN).
YU, Luoting; (CN).
TAO, Xin; (CN)
Agent: SHANGHAI BESHINING LAW OFFICE; 21st Floor, SFECO Mansion, No.681 Xiaomuqiao Road Shanghai 200032 (CN)
Priority Data:
201410058355.6 21.02.2014 CN
Title (EN) THIOPHENE AS HEPATITIS C VIRUS INHIBITOR OR VARIANT DERIVATIVE THEREOF AND USE THEREOF FOR DRUG PREPARATION
(FR) THIOPHÈNE COMME INHIBITEUR DU VIRUS DE L’HÉPATITE C OU SON DÉRIVÉ VARIANT ET SON UTILISATION POUR LA PRÉPARATION DE MÉDICAMENTS
(ZH) 作为丙肝病毒抑制剂的噻吩或其变体衍生物及其制药用途
Abstract: front page image
(EN)Disclosed is a thiophene series as hepatitis C virus (HCV) inhibitors or variant derivatives thereof and compositions thereof, and the present invention relates to the application thereof in preparing chronic hepatitis C virus infection drugs. Particularly, the present invention relates to a series of compounds used as NS5A inhibitors and compositions thereof and uses thereof for drug preparation.
(FR)La présente invention concerne une série de thiophènes comme inhibiteurs du virus de l'hépatite C (VHC) ou leurs dérivés variants et leurs compositions, ainsi que leur application dans la préparation de médicaments contre l'infection chronique causée par le virus de l'hépatite C. La présente invention concerne particulièrement une série de composés employés comme inhibiteurs NS5A et leurs compositions et leurs utilisations pour la préparation de médicaments.
(ZH)本发明公开了一系列作为丙型肝炎病毒(HCV)抑制剂的噻吩或其变体衍生物及其组合物,并涉及其在制备治疗慢性丙型肝炎病毒感染药物中的应用。具体地,本发明涉及作为NS5A抑制剂的系列化合物及其组合物和制药用途。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)