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1. (WO2015123437) CYCLOPROPYLAMINES AS LSD1 INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/123437    International Application No.:    PCT/US2015/015663
Publication Date: 20.08.2015 International Filing Date: 12.02.2015
IPC:
C07D 401/04 (2006.01), C07D 403/04 (2006.01), C07D 205/04 (2006.01), C07D 211/34 (2006.01), A61K 31/397 (2006.01), A61K 31/4418 (2006.01), A61K 31/444 (2006.01), A61K 31/4155 (2006.01), A61K 31/506 (2006.01), A61P 35/00 (2006.01)
Applicants: INCYTE CORPORATION [US/US]; 1801 Augustine Cut-Off Wilmington, Delaware 19803 (US)
Inventors: WU, Liangxing; (US).
HE, Chunhong; (US).
QIAN, Ding-Quan; (US).
SHEN, Bo; (US).
YAO, Wenqing; (US)
Agent: GODDARD, Christine A.; (US)
Priority Data:
61/939,492 13.02.2014 US
62/061,268 08.10.2014 US
Title (EN) CYCLOPROPYLAMINES AS LSD1 INHIBITORS
(FR) CYCLOPROPYLAMINES EN TANT QU'INHIBITEURS DE LSD1
Abstract: front page image
(EN)The present invention is directed to cyclopropylamine derivatives of formula I which are LSDl inhibitors useful in the treatment of diseases such as cancer.
(FR)La présente invention concerne des dérivés de cyclopropylamine de formule I qui sont des inhibiteurs de LSD1 utiles dans le traitement de maladies telles que le cancer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)