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1. (WO2015123434) SOLID FORMS OF AN ION CHANNEL MODULATOR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/123434    International Application No.:    PCT/US2015/015652
Publication Date: 20.08.2015 International Filing Date: 12.02.2015
IPC:
C07D 413/06 (2006.01), A61K 31/553 (2006.01), A61P 9/00 (2006.01)
Applicants: GILEAD SCIENCES, INC. [US/US]; 333 Lakeside Drive Foster City, CA 94404 (US)
Inventors: CHIU, Anna; (US).
LAPINA, Olga V.; (US).
VLAHOVA, Petinka I.; (US)
Agent: GINAH, Francis O.; (US)
Priority Data:
61/939,640 13.02.2014 US
Title (EN) SOLID FORMS OF AN ION CHANNEL MODULATOR
(FR) FORMES SOLIDES D'UN MODULATEUR DE CANAL IONIQUE
Abstract: front page image
(EN)Crystalline solid forms of the selective late sodium current inhibitor 4-(pyrimidin-2-ylmethyl)-7- (4-(trifluoromethoxy)phenyl)-3,4-dihydrobenzo[f][l,4]oxazepin-5(2H)-one (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the crystalline forms.
(FR)L'invention concerne des formes solides cristallines de l'inhibiteur sélectif du courant sodique tardif 4-(pyrimidin-2-ylméthyl)-7-(4-(trifluorométhoxy)phényl)-3,4-dihydrobenzo[f][1,4]oxazépin-5(2H)-one, qui ont été préparées et caractérisées à l'état solide : (composé I). L'invention concerne également des procédés de fabrication et des méthodes d'utilisation de ces formes cristallines.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)