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1. (WO2015123003) BIFUNCTIONAL COMPOUNDS AND USE FOR REDUCING URIC ACID LEVELS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/123003    International Application No.:    PCT/US2015/012370
Publication Date: 20.08.2015 International Filing Date: 22.01.2015
IPC:
A61K 31/513 (2006.01), C07D 401/00 (2006.01)
Applicants: WARRELL, Raymond P. [US/US]; (US)
Inventors: WARRELL, Raymond P.; (US).
PIWINSKI, John J.; (US)
Agent: FUGIT, Donna R.; (US)
Priority Data:
61/939,818 14.02.2014 US
Title (EN) BIFUNCTIONAL COMPOUNDS AND USE FOR REDUCING URIC ACID LEVELS
(FR) COMPOSÉS BIFONCTIONNELS ET LEUR UTILISATION POUR RÉDUIRE LES TAUX D'ACIDE URIQUE
Abstract: front page image
(EN)Bifunctional compounds that increase uric acid excretion and reduce uric acid production. Methods of using these compounds for reducing uric acid levels in blood or serum, for treating disorders of uric acid metabolism, and for maintaining normal uric acid levels in blood or serum are provided. Pharmaceutical compositions comprising the bifunctional compounds are also provided.
(FR)L'invention concerne des composés bifonctionnels qui augmentent l'excrétion de l'acide urique et réduisent la production d'acide urique. L'invention concerne également des procédés d'utilisation de ces composés pour réduire les taux d'acide urique dans le sang ou le sérum, pour traiter des troubles du métabolisme de l'acide urique, et pour maintenir des niveaux d'acide urique normaux dans le sang ou le sérum. La présente invention concerne en outre des compositions pharmaceutiques comprenant les composés bifonctionnels.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)