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1. (WO2015122518) NASAL VACCINE FOR STREPTOCOCCUS PNEUMONIAE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/122518    International Application No.:    PCT/JP2015/054146
Publication Date: 20.08.2015 International Filing Date: 16.02.2015
IPC:
A61K 39/09 (2006.01), A61K 9/06 (2006.01), A61K 47/36 (2006.01), A61P 31/04 (2006.01)
Applicants: LSIP, LLC [JP/JP]; 7-12, Marunouchi 1-chome, Chiyoda-ku, Tokyo 1000005 (JP)
Inventors: YUKI, Yoshikazu; (JP).
KIYONO, Hiroshi; (JP).
AKIYOSHI, Kazunari; (JP).
SAWADA, Shinichi; (JP)
Agent: AKIYAMA, Atsushi; (JP)
Priority Data:
2014-027205 17.02.2014 JP
Title (EN) NASAL VACCINE FOR STREPTOCOCCUS PNEUMONIAE
(FR) VACCIN NASAL CONTRE STREPTOCOCCUS PNEUMONIAE
(JA) 肺炎球菌経鼻ワクチン
Abstract: front page image
(EN)The present invention provides a nasal vaccine for Streptococcus pneumoniae, and a production method therefor. This nasal vaccine formulation for primates includes a complex of PspA, i.e. the vaccine antigen, and a nanogel in which hydrophobic cholesterol is added, as a side chain, to pullulan having amino groups. Furthermore, the present invention provides a production method for the nasal vaccine formulation for primates.
(FR)La présente invention concerne un vaccin nasal contre Streptococcus pneumoniae, et son procédé de fabrication. Ladite formulation de vaccin nasal pour primates comprend un complexe constitué de PspA, c'est-à-dire l'antigène du vaccin, et d'un nanogel, auquel du cholestérol hydrophobe est ajouté en tant que chaîne latérale à du pullulane possédant des groupes amino. En outre, la présente invention concerne un procédé de fabrication de ladite formulation de vaccin nasal pour primates.
(JA) 本発明は、肺炎球菌経鼻ワクチン及びその製造方法を提供する。 本発明は、アミノ基を有するプルランに側鎖として疎水性のコレステロールを付加したナノゲルとワクチン抗原であるPspAとの複合体を含む霊長類用経鼻ワクチン製剤である。また、本発明は、前記霊長類経鼻ワクチン製剤の製造方法である。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)