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1. (WO2015121457) FGF-8 FOR USE IN TREATING DISEASES OR DISORDERS OF ENERGY HOMEOSTASIS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2015/121457 International Application No.: PCT/EP2015/053165
Publication Date: 20.08.2015 International Filing Date: 13.02.2015
IPC:
A61K 38/18 (2006.01) ,A61P 3/00 (2006.01) ,A61P 3/08 (2006.01) ,A61P 3/10 (2006.01) ,A61P 3/06 (2006.01) ,A61K 8/64 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
18
Growth factors; Growth regulators
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
08
for glucose homeostasis
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
08
for glucose homeostasis
10
for hyperglycaemia, e.g. antidiabetics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3
Drugs for disorders of the metabolism
06
Antihyperlipidemics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
30
containing organic compounds
64
Proteins; Peptides; Derivatives or degradation products thereof
Applicants:
TECHNISCHE UNIVERSITÄT MÜNCHEN [DE/DE]; DE
Inventors:
WESTPHAL, Sören; DE
FROMME, Tobias; DE
KLINGENSPOR, Martin; DE
Agent:
MEIER, Jürgen; Vossius & Partner Siebertstraße 3 81675 München, DE
Priority Data:
14155088.913.02.2014EP
Title (EN) FGF-8 FOR USE IN TREATING DISEASES OR DISORDERS OF ENERGY HOMEOSTASIS
(FR) FGF-8 DESTINÉ À ÊTRE UTILISÉ DANS LE TRAITEMENT DE MALADIES OU DE TROUBLES DE L'HOMÉOSTASIE ÉNERGÉTIQUE
Abstract:
(EN) The present invention relates to polypeptides for use in treating diseases or disorders of energy homeostasis such as obesity, dyslipidemia, diabetes, insulin resistance, hyperglycemia or the metabolic syndrome. The invention also relates to polynucleotides encoding said polypeptides for use in treating diseases or disorders of energy homeostasis. Also provided by the present invention are pharmaceutical compositions comprising said polypeptides and polynucleotides for use in treating diseases or disorders of energy homeostasis. Said polypeptides, polynucleotides and pharmaceutical compositions may be administered locally, in particular locally into the visceral adipose tissue. Another aspect of the invention relates to a cosmetic product and the use of said cosmetic product for reducing body weight, in particular for reducing abdominal adipose tissue.
(FR) La présente invention concerne des polypeptides destinés à être utilisés dans le traitement de maladies ou de troubles de l'homéostasie énergétique tels que l'obésité, la dyslipidémie, le diabète, la résistance à l'insuline, l'hyperglycémie ou le syndrome métabolique. L'invention concerne également des polynucléotides codant pour lesdits polypeptides destinés à être utilisés dans le traitement de maladies ou de troubles de l'homéostasie énergétique. La présente invention décrit également des compositions pharmaceutiques comprenant lesdits polypeptides et polynucléotides destinés à être utilisés dans le traitement de maladies ou de troubles de l'homéostasie énergétique. Lesdits polypeptides, polynucléotides et compositions pharmaceutiques peuvent être administrés localement, en particulier localement dans le tissu adipeux viscéral. Un autre aspect de l'invention concerne un produit cosmétique et l'utilisation dudit produit cosmétique pour diminuer le poids corporel, en particulier pour diminuer le tissu adipeux abdominal.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)