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1. (WO2015121383) BISPECIFIC ANTIBODIES FOR USE IN STEM CELL TRANSPLANTATION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2015/121383 International Application No.: PCT/EP2015/053026
Publication Date: 20.08.2015 International Filing Date: 12.02.2015
IPC:
C07K 16/28 (2006.01)
Applicants: UHLIN, Michael[SE/SE]; SE
MATTSSON, Jonas[SE/SE]; SE
Inventors: UHLIN, Michael; SE
MATTSSON, Jonas; SE
Agent: SMITH, Stephen Edward; GB
Priority Data:
61/938,79112.02.2014US
Title (EN) BISPECIFIC ANTIBODIES FOR USE IN STEM CELL TRANSPLANTATION
(FR) ANTICORPS BISPÉCIFIQUES UTILISABLES DANS UNE TRANSPLANTATION DE CELLULES SOUCHES
Abstract: front page image
(EN) New monoclonal antibodies for use in pre-treatments prior to stem cell transplantations are disclosed. The antibodies may be used to kill malignant cells and/or stem cells prior to stem cell transplantation. The antibodies can be used for treating hematologic diseases and hematological malignancies, such as leukemia and MDS. The antibodies of the invention might be multi- or bi-specific, such as BiTEs.
(FR) L'invention concerne de nouveaux anticorps monoclonaux qui s'utilisent dans des pré-traitements, avant transplantation de cellules souches. Ces anticorps peuvent être utilisés pour tuer des cellules malignes et/ou des cellules souches, avant transplantation de cellules souches. Les anticorps peuvent être utilisés pour traiter des maladies hématologiques ou des tumeurs malignes hématologiques, telles que la leucémie et le syndrome myélodisplasique (MDS). Les anticorps de l'invention peuvent être multispécifiques ou bispécifiques, tels que des BiTE.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)