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1. (WO2015120799) SUCCINOBUCOL NANOSUSPENSION AND PREPARATION METHOD THEREFOR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/120799    International Application No.:    PCT/CN2015/072801
Publication Date: 20.08.2015 International Filing Date: 11.02.2015
IPC:
A61K 9/10 (2006.01), A61K 31/225 (2006.01), A61P 3/06 (2006.01), A61P 9/10 (2006.01)
Applicants: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES [CN/CN]; 555 Zuchongzhi Road, Zhangjiang, Pudong Shanghai 201203 (CN)
Inventors: LI, Yaping; (CN).
ZHANG, Zhiwen; (CN)
Agent: KINGSOUND & PARTNERS; 11/F, Block B, KingSound International Center, 116 Zizhuyuan Road, Haidian District Beijing 100097 (CN)
Priority Data:
201410048877.8 12.02.2014 CN
Title (EN) SUCCINOBUCOL NANOSUSPENSION AND PREPARATION METHOD THEREFOR
(FR) NANOSUSPENSION DE SUCCINOBUCOL ET SON PROCÉDÉ DE PRÉPARATION
(ZH) 一种琥珀布考纳米混悬液及其制备方法
Abstract: front page image
(EN)A succinobucol nanosuspension and a preparation method therefor. The succinobucol nanosuspension contains 1 part of succinobucol, 0.1-1000 parts of a surfactant and 0-100000 parts of water, and has a grain size of 10-200 nm. The succinobucol nanosuspension is prepared by a thin-film hydration method, a spray drying method or a grinding method. The succinobucol nanosuspension enables a drug to be easily absorbed in the body and helps to improve the bioavailability of the drug.
(FR)L'invention concerne une nanosuspension de succinobucol et son procédé de préparation. Cette nanosuspension de succinobucol comprend 1 partie de succinobucol, 0,1-1000 partie(s) d'un tensioactif et 0-100 000 partie(s) d'eau, la granulométrie étant de 10-200 nm. Cette nanosuspension de succinobucol est obtenue par hydratation-membrane, par séchage par pulvérisation ou par abrasion. Elle facilite l'absorption du médicament dans le corps et favorise sa biodisponibilité.
(ZH)一种琥珀布考纳米混悬液及其制备方法。所述琥珀布考纳米混悬液含琥珀布考1份、表面活性剂0.1-1000份和水0-100000份,粒径为10-200nm。所述琥珀布考纳米混悬液采用薄膜-水化法、喷雾干燥法或研磨法制备。所述琥珀布考纳米混悬液使药物在体内容易被吸收,有利于提高药物的生物利用度。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)