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Machine translation
1. (WO2015120730) THIOCHROMENO[2,3-C]QUINOLIN-12-ONE DERIVATIVES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/120730    International Application No.:    PCT/CN2014/089182
Publication Date: 20.08.2015 International Filing Date: 22.10.2014
IPC:
C07D 513/04 (2006.01), A61K 31/4365 (2006.01), A61P 35/02 (2006.01), A61P 35/04 (2006.01)
Applicants: HUANG, Hsu-Shan [CN/CN]; (CN)
Inventors: HUANG, Hsu-Shan; (CN).
YU, Dah-Shyong; (CN).
CHEN, Tsung-Chih; (CN)
Agent: ADVANCE CHINA IP LAW OFFICE; Room 3901, No.85 Huacheng Avenue, Tianhe District Guangzhou, Guangdong 510623 (CN)
Priority Data:
14/180,707 14.02.2014 US
Title (EN) THIOCHROMENO[2,3-C]QUINOLIN-12-ONE DERIVATIVES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
(FR) DÉRIVÉS DE THIOCHROMÉNO[2,3-C]QUINOLIN-12-ONE, LEUR PROCÉDÉ DE PRÉPARATION ET LEUR APPLICATION
(ZH) 脱氢硫胺[2,3-c]喹啉-12-酮衍生物及其制备方法和应用
Abstract: front page image
(EN)Disclosed are a series of novel thiochromeno[2,3-c]quinolin-12-one derivatives, and also provided are a preparation method for the derivatives and an application of the derivatives. The application comprises preparing said derivatives into pharmaceutical compositions for treating cancer, and the application comprises that said derivatives are capable of significantly inhibiting cancel cell growth and inhibiting type I and II topoisomerase activity and further treating cancer.
(FR)L'invention concerne une série de nouveaux dérivés de thiochroméno[2,3-c]quinolin-12-one, et concerne également un procédé de préparation des dérivés et une application des dérivés. L'application comprend la préparation desdits dérivés en compositions pharmaceutiques pour le traitement du cancer, et l'application comprend le fait que lesdits dérivés sont capables d'inhiber significativement la croissance des cellules cancéreuses et d'inhiber l'activité des topo-isomérases de type I et de type II et de traiter en outre le cancer.
(ZH)本发明公开了一系列新颖脱氢硫胺[2,3-c]喹啉-12-酮衍生物,并进一步提供该些衍生物的制备方法及其应用,该应用包含将该类衍生物作为治疗癌症的医药组合物,且其应用包含该类衍生物具有明显抑制癌细胞生长的能力、抑制第一、二型拓朴异构酶的活性,进而治疗癌症等功效。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)