WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2015120536) PEPTIDES THAT BLOCK LEUKOCYTE RECRUITMENT AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/120536    International Application No.:    PCT/CA2015/000078
Publication Date: 20.08.2015 International Filing Date: 13.02.2015
IPC:
C07K 7/08 (2006.01), A61K 38/10 (2006.01), A61K 47/48 (2006.01), A61P 31/00 (2006.01), A61P 35/00 (2006.01), A61P 35/04 (2006.01), A61P 37/02 (2006.01), C07K 1/113 (2006.01), C12Q 1/00 (2006.01), C40B 30/04 (2006.01), C40B 30/06 (2006.01), G01N 33/53 (2006.01)
Applicants: ARCH CANCER THERAPEUTICS, INC. [CA/CA]; 388 Point McKay Gardens Calgary, Alberta T2B 4V8 (CA)
Inventors: ROBBINS, Stephen, Mark; (CA).
SENGER, Donna, L.; (CA).
RAHN, Jennifer, Joy; (CA).
KUBES, Paul; (CA)
Agent: WILKIE, Jennifer, L.; Gowling WLG (Canada) LLP 160 Elgin Street, Suite 2600 Ottawa, Ontario K1P 1C3 (CA)
Priority Data:
61/939,561 13.02.2014 US
Title (EN) PEPTIDES THAT BLOCK LEUKOCYTE RECRUITMENT AND METHODS OF USE
(FR) PEPTIDES QUI BLOQUENT LE RECRUTEMENT DES LEUCOCYTES, ET PROCÉDÉS D'UTILISATION
Abstract: front page image
(EN)Disclosed are novel peptides comprising SEQ ID NO: 1 and modifications thereof, which are effective in blocking leukocyte recruitment. The disclosed peptides are useful for treating diseases associated with leukocyte recruitment for example inhibiting metastasis of a solid tumor to the liver and lungs and for treating sepsis. Also disclosed are methods of screening for compounds having the ability to block leukocyte recruitment.
(FR)L'invention concerne de nouveaux peptides comprenant SEQ ID NO: 1 et des modifications de cette dernière, qui sont efficaces pour bloquer le recrutement des leucocytes. Les peptides exposés sont utiles pour le traitement de maladies associées au recrutement des leucocytes, par exemple pour inhiber la métastase d'une tumeur solide vers le foie et les poumons, et pour traiter une sepsie. L'invention concerne aussi des procédés de criblage portant sur des composés ayant la capacité de bloquer le recrutement des leucocytes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)