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1. (WO2015120237) 4'-DIFLUOROMETHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF INFLUENZA RNA REPLICATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/120237    International Application No.:    PCT/US2015/014762
Publication Date: 13.08.2015 International Filing Date: 06.02.2015
IPC:
A61K 31/7052 (2006.01), A61K 31/7072 (2006.01), C07H 19/04 (2006.01)
Applicants: RIBOSCIENCE LLC [US/US]; 3901 Laguna Avenue Palo Alto, California 94306 (US)
Inventors: SMITH, Mark; (US).
KLUMPP, Klaus G.; (US)
Agent: KISKO, Jennifer L.; (US)
Priority Data:
61/936,569 06.02.2014 US
Title (EN) 4'-DIFLUOROMETHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF INFLUENZA RNA REPLICATION
(FR) DÉRIVÉS DE NUCLÉOSIDES À SUBSTITUTION 4'-DIFLUOROMÉTHYLE UTILISÉS EN TANT QU'INHIBITEURS DE LA RÉPLICATION DE L'ARN DU VIRUS DE LA GRIPPE
Abstract: front page image
(EN)The application discloses nucleoside derivatives of Formula I as inhibitors of Influenza RNA replication. In particular, the application discloses the use of purine and pyrimidine nucleoside derivatives of Formula I as inhibitors of Influenza RNA replication and pharmaceutical compositions containing such compounds.
(FR)L'invention concerne des dérivés de nucléosides représentés par la formule I à utiliser en tant qu'inhibiteurs de la réplication d'ARN du virus de la grippe. La présente invention concerne en particulier l'utilisation de dérivés de nucléosides de purine et de pyrimidine de formule I en tant qu'inhibiteurs de la réplication de l'ARN du virus de la grippe ainsi que des compositions pharmaceutiques contenant de tels composés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)