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1. (WO2015120185) NOVEL ASSAY TO DETECT HUMAN PERIOSTIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/120185    International Application No.:    PCT/US2015/014671
Publication Date: 13.08.2015 International Filing Date: 05.02.2015
IPC:
G01N 33/68 (2006.01), C07K 16/18 (2006.01)
Applicants: MEDIMMUNE, LLC [US/US]; One Medimmune Way Gaithersburg, Maryland 20878 (US).
ABBOTT LABORATORIES [--/US]; 100 Abbott Park Road, Patent & Trademark Dept., D377, Ap6a-1 Abbott Park, Illinois 60064 (US)
Inventors: CHOWDHURY, Partha; (US).
VARKEY, Reena; (US).
LIANG, Meina; (US).
LEE, Yen-Wah; (US).
STREICHER, Katie; (US).
RANADE, Koustubh; (US).
GRANT, Ethan; (US).
GREENLEES, Lydia; (US).
YAO, Yihong; (US).
PARKER, Melissa; (US).
DAVIS, Gerard; (US).
JEANBLANC, Nicolette; (US).
BROPHY, Susan; (US).
DILLE, Bruce; (US)
Agent: MUELLER, Lisa; (US)
Priority Data:
61/936,967 07.02.2014 US
Title (EN) NOVEL ASSAY TO DETECT HUMAN PERIOSTIN
(FR) NOUVEL ESSAI BIOLOGIQUE POUR LA DETECTION DE LA PERIOSTINE HUMAINE
Abstract: front page image
(EN)This disclosure provides a robust, sensitive, and specific assay for the detection and measurement of periostin levels in samples obtained from human patients having, or suspected of having an IL-13-mediated disease or disorder. The disclosure further provides novel antiperiostin monoclonal antibodies that recognize at least isoforms 1, 2, 3, 4, 7, and 8 of human periostin, and assay kits comprising one or more of these antibodies.
(FR)La présente invention concerne un essai biologique robuste, sensible, et spécifique pour la détection et la mesure de niveaux de la périostine dans des échantillons obtenus à partir de patients humains atteints, ou suspectés d'être atteints par une maladie ou d'un trouble provoqué(e) par l'IL -13. L'invention concerne également de nouveaux anticorps monoclonaux anti-périostine qui reconnaissent au moins des isoformes 1, 2, 3, 4, 7 et 8 de la périostine humaine, et des trousses d'essai biologique comportant un ou plusieurs de ces anticorps.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)