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1. (WO2015120065) GAMMA-SECRETASE INHIBITION REDUCE APOC3 LEVELS AND PLASMA TRIGLYCERIDES

Pub. No.:    WO/2015/120065    International Application No.:    PCT/US2015/014481
Publication Date: Fri Aug 14 01:59:59 CEST 2015 International Filing Date: Thu Feb 05 00:59:59 CET 2015
IPC: C12P 19/34
C12N 15/00
C07H 21/02
C07H 19/00
C07H 21/00
Applicants: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
PAJVANI, Utpal
Inventors: PAJVANI, Utpal
Title: GAMMA-SECRETASE INHIBITION REDUCE APOC3 LEVELS AND PLASMA TRIGLYCERIDES
Abstract:
A method of reducing a subject's plasma triglyceride level, comprising administering to a subject in need thereof a gamma-secretase inhibitor in an amount effective to reduce the subject' s plasma triglyceride level.