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1. (WO2015119995) GUIDED DIFFERENTIATION OF INDUCED PLURIPOTENT STEM CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2015/119995 International Application No.: PCT/US2015/014377
Publication Date: 13.08.2015 International Filing Date: 04.02.2015
IPC:
C12N 5/00 (2006.01) ,C12N 5/071 (2010.01) ,A01N 63/00 (2006.01)
Applicants: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH[US/US]; 200 First Street S.W. Rochester, Minnesota 55905, US
Inventors: IKEDA, Yasuhiro; US
EL KHATIB, Moustafa M.A.; US
Agent: FINN III, J. Patrick; US
Priority Data:
61/935,94405.02.2014US
Title (EN) GUIDED DIFFERENTIATION OF INDUCED PLURIPOTENT STEM CELLS
(FR) DIFFÉRENTIATION GUIDÉE DE CELLULES SOUCHES PLURIPOTENTES INDUITES
Abstract:
(EN) This document provides methods and materials related to making and using differentiated induced pluripotent stem cells. For example, methods and materials for making differentiated induced pluripotent stem cells (e.g., insulin-producing cells) that do not form cancer cells within a mammal (e.g., a human), cells that underwent guided differentiation from induced pluripotent stem cells, compositions containing cells that underwent guided differentiation from induced pluripotent stem cells, and methods for using cells that underwent guided differentiation from induced pluripotent stem cells (e.g., methods for using such cells to treat diabetes or to repair cardiovascular tissue) are provided.
(FR) L'invention concerne les procédés et matériaux associés à la fabrication et l'utilisation de cellules souches pluripotentes induites différenciées. L'invention concerne par exemple des procédés et matériaux permettant de produire des cellules souches pluripotentes induites différenciées (par exemple, des cellules productrices d'insuline) qui ne se transforment pas en cellules cancéreuses chez les mammifères (par exemple, chez l'humain), des cellules produites par différenciation guidée de cellules souches pluripotentes induites, des compositions contenant des cellules produites par différenciation guidée de cellules souches pluripotentes induites, et les modes d'utilisation des cellules produites par différenciation guidée de cellules souches pluripotentes induites (par exemple, des modes d'utilisation de telles cellules dans le traitement du diabète ou pour réparer le tissu cardiovasculaire).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)