Search International and National Patent Collections

1. (WO2015119470) PCR DEVICE PROVIDED WITH UNIDIRECTIONAL SLIDING MEANS AND PCR METHOD USING SAME

Pub. No.:    WO/2015/119470    International Application No.:    PCT/KR2015/001291
Publication Date: Fri Aug 14 01:59:59 CEST 2015 International Filing Date: Tue Feb 10 00:59:59 CET 2015
IPC: C12M 1/38
C12Q 1/68
Applicants: NANOBIOSYS INC.
나노바이오시스 주식회사
Inventors: KIM, Sung Woo
김성우
Title: PCR DEVICE PROVIDED WITH UNIDIRECTIONAL SLIDING MEANS AND PCR METHOD USING SAME
Abstract:
One embodiment of the present invention relates to a PCR device provided with a unidirectional sliding means and a PCR method using same. According to the present invention, the amount of samples treated can be increased by simultaneously, rapidly, and accurately performing a PCR on a large number of samples through sequential thermal contact between a thermal block in which at least two heaters are repeatedly arranged and a PCR chip in which at least two reaction chambers are repeatedly arranged. Also, the present invention is capable of: significantly improving PCR yield by preventing radial heat distribution generated by each heater and consequent non-uniform thermal overlap between adjacent heaters; significantly contributing to size reduction and integration of the device by not requiring a separate temperature control means; simultaneously and rapidly amplifying multiple nucleic acid samples by using the thermal block in which heater units are repeatedly arranged and a plate-shaped PCR reacting portion; and confirming a nucleic acid amplifying step in real time by measuring continuous optical signals or electrochemical signals.