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1. (WO2015118547) METHOD OF MAINTAINING DISEASE STABILITY IN A SUBJECT HAVING GAUCHER'S DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/118547    International Application No.:    PCT/IL2015/050145
Publication Date: 13.08.2015 International Filing Date: 09.02.2015
IPC:
A61K 38/47 (2006.01), C12N 9/24 (2006.01), C12N 15/82 (2006.01), A61K 36/23 (2006.01), A61P 43/00 (2006.01)
Applicants: PROTALIX LTD. [IL/IL]; 2 Snunit Street Science Park 2010000 Carmiel (IL)
Inventors: SHAALTIEL, Yoseph; (IL).
ALMON, Einat; (IL)
Agent: G. E. EHRLICH (1995) LTD.; 11 Menachem Begin Road 5268104 Ramat Gan (IL)
Priority Data:
61/937,901 10.02.2014 US
Title (EN) METHOD OF MAINTAINING DISEASE STABILITY IN A SUBJECT HAVING GAUCHER'S DISEASE
(FR) MÉTHODE DE MAINTIEN DE LA STABILITÉ D'UNE MALADIE CHEZ UN SUJET ATTEINT DE LA MALADIE DE GAUCHER
Abstract: front page image
(EN)A method of maintaining disease stability in a subject having Gaucher's disease following switch from enzyme replacement therapy (ERT) is provided. The method comprising orally administering to the subject a therapeutically effective amount of recombinant glucocerebrosidase (GCD) comprised in plant cells, thereby maintaining disease stability following switch.
(FR)On décrit une méthode de maintien de la stabilité d'une maladie chez un sujet atteint de la maladie de Gaucher, suite à une commutation d'une thérapie de remplacement enzymatique (ERT). La méthode consiste à administrer au sujet, par voie orale, une quantité thérapeutiquement efficace de glucocérébrosidase recombinante (GCD) présente dans des cellules végétales, ce qui permet de maintenir la stabilité de la maladie à la suite d'une commutation.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)