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1. (WO2015118124) THYMIC STROMAL LYMPHOPOIETIN RECEPTOR ANTAGONIST
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/118124    International Application No.:    PCT/EP2015/052546
Publication Date: 13.08.2015 International Filing Date: 06.02.2015
IPC:
A61K 38/00 (2006.01), C07K 14/715 (2006.01), C07K 16/24 (2006.01)
Applicants: VIB VZW [BE/BE]; Rijvisschestraat 120 B-9052 Gent (BE).
UNIVERSITEIT GENT [BE/BE]; Sint-Pietersnieuwstraat 25 B-9000 Gent (BE)
Inventors: PEELMAN, Frank; (BE).
SAVVIDES, Savvas; (BE).
VERSTRAETE, Kenneth; (BE)
Common
Representative:
VIB VZW; Rijvisschestraat 120 B-9052 Gent (BE)
Priority Data:
14154134.2 06.02.2014 EP
Title (EN) THYMIC STROMAL LYMPHOPOIETIN RECEPTOR ANTAGONIST
(FR) ANTAGONISTE DU RÉCEPTEUR DE LA LYMPHOPOÏÉTINE STROMALE THYMIQUE
Abstract: front page image
(EN)The present invention relates to a Thymic Stromal Lymphopoietin Receptor antagonist. More specifically, it relates to a mutant form of Thymic Stromal Lymphopoietin, capable of binding the receptor, but unable to induce signaling. The invention relates further to the use of the antagonist to treat inflammatory disorders.
(FR)L'invention concerne un antagoniste du récepteur de la lymphopoïétine stromale thymique. Elle concerne plus particulièrement une forme mutante de la lymphopoïétine stromale thymique, qui peut se lier au récepteur mais est incapable d'induire la signalisation. Elle concerne en outre l'utilisation de l'antagoniste pour traiter des troubles inflammatoires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)