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1. (WO2015118045) MEMBRANE FOR BLOOD PURIFICATION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2015/118045 International Application No.: PCT/EP2015/052364
Publication Date: 13.08.2015 International Filing Date: 05.02.2015
IPC:
B01D 63/02 (2006.01) ,B01D 69/08 (2006.01) ,B01D 71/44 (2006.01) ,B01D 71/68 (2006.01) ,A61M 1/16 (2006.01)
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
63
Apparatus in general for separation processes using semi-permeable membranes
02
Hollow fibre modules
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
69
Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
08
Hollow fibre membranes
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
71
Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
06
Organic material
44
Polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds, not provided for in a single one of groups B01D71/26-B01D71/42177
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
71
Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
06
Organic material
66
Polymers having sulfur in the main chain, with or without nitrogen, oxygen or carbon only
68
Polysulfones; Polyethersulfones
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1
Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
14
Dialysis systems; Artificial kidneys; Blood oxygenators
16
with membranes
Applicants: GAMBRO LUNDIA AB[SE/SE]; P. O. Box 10101 S-220 10 Lund, SE
Inventors: BOSCHETTI-DE-FIERRO, Adriana; DE
VOIGT, Manuel; DE
KRAUSE, Bernd; DE
HORNUNG, Markus; DE
STORR, Markus; DE
BEHR, Heinrich; DE
BECK, Werner; DE
ZWEIGART, Carina; DE
BUCK, Reinhold; DE
HERBST, Philipp; DE
LOERCHER, Joachim; DE
WOCHNER, Arnd; DE
Agent: HORNUNG, Veronika; DE
Priority Data:
14154175.506.02.2014EP
Title (EN) MEMBRANE FOR BLOOD PURIFICATION
(FR) MEMBRANE DE PURIFICATION DU SANG
Abstract:
(EN) The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.
(FR) La présente invention concerne des membranes semi-perméables qui sont appropriées pour la purification du sang, par exemple par hémodialyse, qui ont une capacité accrue à éliminer des molécules plus grosses tout en retenant simultanément l'albumine efficacement. Les membranes sont caractérisées par un début de rétention moléculaire (MWRO) compris entre 9,0 kD et 14,5 kD et un seuil de coupure de poids moléculaire (MWCO) compris entre 55 kD et 130 kD tel que déterminé par des courbes de filtration de dextrane et peuvent être préparées par des processus industriellement faisables en excluant un traitement avec du sel avant le séchage. L'invention concerne en outre un procédé de production des membranes et leur utilisation dans des applications médicales.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)