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|1. (WO2015117538) NEW DAPAGLIFLOZIN CRYSTALLINE FORM AND PREPARATION METHOD THEREFOR|
|Applicants:||JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD.
|Title:||NEW DAPAGLIFLOZIN CRYSTALLINE FORM AND PREPARATION METHOD THEREFOR|
The present invention relates to a new crystalline form of dapagliflozin represented by formula (I). The crystalline form has a characteristic absorption peak at about 4.318(20.45) in X-ray powder diffraction pattern shown by angle 2 theta and interplanar spacing (value d). It can be prepared by solving dapagliflozin into good organic solvents, adding poor solvents, agitating, crystallizing, filtering and drying. The new crystalline form of dapagliflozin of the present invention has the following superior features: good solubility, low hygroscopicity, high stability and good preparation reproducibility.