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1. (WO2015117033) METHODS OF INCREASING PROTEIN PRODUCTION IN MAMMALIAN CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/117033    International Application No.:    PCT/US2015/013982
Publication Date: 06.08.2015 International Filing Date: 30.01.2015
IPC:
C12P 21/02 (2006.01), C12N 15/85 (2006.01)
Applicants: BIOGEN MA INC. [US/US]; 250 Binney Street Cambridge, MA 02142 (US)
Inventors: FOLLIT, John; (US).
ESTES, Scott; (US)
Agent: DIPIETRANTONIO, Heather, J.; (US)
Priority Data:
61/934,661 31.01.2014 US
Title (EN) METHODS OF INCREASING PROTEIN PRODUCTION IN MAMMALIAN CELLS
(FR) MÉTHODES D'AUGMENTATION DE PRODUCTION DE PROTÉINES DANS DES CELLULES DE MAMMIFÈRES
Abstract: front page image
(EN)Aspects of the present disclosure provide compositions and methods for increasing protein production in mammalian cells, e.g. methods of increasing mammalian cell expression of a protein of interest, comprising culturing mammalian cells that overexpress a protein of interest and are modified to overexpress a gene encoding Rab 11 or Yapl, as well as mammalian cells that overexpress a protein of interest and which are modified to overexpress a gene encoding Rab 11 or Yapl.
(FR)Des aspects de la présente invention concernent des compositions et des méthodes pour augmenter la production de protéines dans des cellules de mammifères.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)