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1. (WO2015116782) NUCLEOBASE ANALOGUE DERIVATIVES AND THEIR APPLICATIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/116782    International Application No.:    PCT/US2015/013454
Publication Date: 06.08.2015 International Filing Date: 29.01.2015
IPC:
A61K 31/7068 (2006.01)
Applicants: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM [US/US]; 201 West 7th Street Austin, Texas 78701 (US)
Inventors: CUI, Zhengrong; (US).
LANSAKARA-P., Dharmika; (US)
Agent: CURFMAN, Christopher L.; (US)
Priority Data:
61/933,035 29.01.2014 US
Title (EN) NUCLEOBASE ANALOGUE DERIVATIVES AND THEIR APPLICATIONS
(FR) DÉRIVÉS D'UN ANALOGUE DE NUCLÉOBASE ET LEURS APPLICATIONS
Abstract: front page image
(EN)Disclosed herein are derivatives of nucleobase analogues. The disclosed compounds have a nucleobase moiety and an omega-3 polyunsaturated fatty acid moiety, including pharmaceutically acceptable salt or prodrug thereof. Methods of using these compounds for the treatment of cancers such as pancreatic cancer are also disclosed.
(FR)Cette invention concerne des dérivés d'analogues de nucléobase. Les composés décrits ont une fraction nucléobase et une fraction d'acide gras polyinsaturés oméga-3, y compris un de ses sel ou promédicament pharmaceutiquement acceptable. Des méthodes d'utilisation de ces composés pour le traitement de cancers tels que le cancer du pancréas sont également décrits.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)