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1. (WO2015116778) AVIAN REOVIRUS VACCINES

Pub. No.:    WO/2015/116778    International Application No.:    PCT/US2015/013449
Publication Date: Fri Aug 07 01:59:59 CEST 2015 International Filing Date: Fri Jan 30 00:59:59 CET 2015
IPC: C12N 7/08
C12N 7/00
A61K 39/15
Applicants: UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.
Inventors: SELLERS, Holly, S.
Title: AVIAN REOVIRUS VACCINES
Abstract:
The present invention relates to novel strains of avian reovirus that were isolated from clinical cases of viral arthritis/tenosynovitis in chickens in the southeast United States. The invention is directed to these novel group 1 and group 2 avian reoviruses, diagnostic assays using nucleotide- or amino acid-specific components of such viruses, such as the S1 gene encoding the sigma C protein, and to vaccines that protect chickens from disease caused by such viruses.