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1. (WO2015116539) ANTI-LAG-3 ANTIBODIES TO TREAT HEMATOLOGICAL MALIGNANCIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/116539    International Application No.:    PCT/US2015/012916
Publication Date: 06.08.2015 International Filing Date: 26.01.2015
IPC:
C07K 16/28 (2006.01), A61K 39/395 (2006.01), A61P 35/00 (2006.01), A61P 35/02 (2006.01)
Applicants: BRISTOL-MYERS SQUIBB COMPANY [US/US]; Route 206 & Province Line Road Princeton, NJ 08543 (US)
Inventors: GUTIERREZ, Andres, A.; (US).
GROSSO, Joseph; (US).
HILL, Christopher, Mark; (US).
SELBY, Mark; (US).
LEWIS, Katherine E.; (US)
Agent: REMILLARD, Jane, E.; (US)
Priority Data:
61/932,589 28.01.2014 US
Title (EN) ANTI-LAG-3 ANTIBODIES TO TREAT HEMATOLOGICAL MALIGNANCIES
(FR) ANTICORPS ANTI-LAG-3 POUR TRAITER DES HÉMOPATHIES MALIGNES
Abstract: front page image
(EN)Provided are methods for clinical treatment of hematological malignancies, such as relapsed or refractory chronic lymphocytic leukemia or lymphoma using an anti-LAG-3 antibody. Particular malignancies include, e.g., chronic lymphocytic leukemia (CLL), Hodgkin lymphoma (HL), or non-Hodgkin lymphoma (NHL).
(FR)L'invention concerne des procédés pour le traitement clinique d'hémopathies malignes, telles qu'un lymphome ou une leucémie lymphoïde chronique réfractaire ou récurrente à l'aide d'un anticorps anti-LAG-3. Parmi les affections malignes particulières, on compte, p. ex., la leucémie lymphoïde chronique (LLC), le lymphome de Hodgkin (HL), ou le lymphome non-hodgkinien (NHL).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)