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Machine translation
1. (WO2015115853) PHARMACEUTICAL COMPOSITION INCLUDING 5-{4-(AMINOSULFONYL)PHENYL}-2,2-DIMETHYL-4-(3-FLUOROPHENYL)-3(2H)-FURANONE AND CAPSULE FORMULATION INCLUDING THE PHARMACEUTICAL COMPOSITION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2015/115853 International Application No.: PCT/KR2015/001002
Publication Date: 06.08.2015 International Filing Date: 29.01.2015
IPC:
A61K 31/34 (2006.01) ,A61K 31/255 (2006.01) ,A61K 9/48 (2006.01) ,A61K 47/38 (2006.01)
Applicants: CRYSTALGENOMICS, INC.[KR/KR]; 700, Daewangpangyo-ro Bundang-gu Seongnam-si Gyeonggi-do 463-400, KR
Inventors: KIM, Byung-Ha; KR
AHN, Sik Il; KR
PARK, Jae-Yeon; KR
KIM, Tae Ryong; KR
CHO, Joong Myung; KR
RO, Seonggu; KR
Agent: KIM, Aera; KR
Priority Data:
10-2014-001131529.01.2014KR
Title (EN) PHARMACEUTICAL COMPOSITION INCLUDING 5-{4-(AMINOSULFONYL)PHENYL}-2,2-DIMETHYL-4-(3-FLUOROPHENYL)-3(2H)-FURANONE AND CAPSULE FORMULATION INCLUDING THE PHARMACEUTICAL COMPOSITION
(FR) COMPOSITION PHARMACEUTIQUE COMPRENANT DE LA 5-{4-(AMINOSULFONYL)PHÉNYL}-2,2-DIMÉTHYL-4-(3(FLUOROPHÉNYL)-3(2H)-FURANONE ET CAPSULE COMPRENANT LA COMPOSITION PHARMACEUTIQUE
Abstract: front page image
(EN) The present invention relates to a pharmaceutical composition including (i) the compound of Formula 1 described in the specification or a pharmaceutically acceptable salt thereof, (ii) a pharmaceutically acceptable diluent, and (iii) a pharmaceutically acceptable lubricant. The compound of Formula 1 or pharmaceutically acceptable salt thereof has a 50% volume particle diameter (d(0.5)) of 3 μm to 9 μm. The pharmaceutical composition of the present invention has the advantages of good stability, high dissolution rate, improved content uniformity, and excellent pharmacokinetic properties. Due to these advantages, the pharmaceutical composition of the present invention is effective in treating inflammation or pain.
(FR) La présente invention concerne une composition pharmaceutique comprenant (i) le composé de formule 1 décrit dans la description ou son sel pharmaceutiquement acceptable, (ii) un diluant pharmaceutiquement acceptable et (iii) un lubrifiant pharmaceutiquement acceptable. Le composé de la formule 1 ou son sel pharmaceutiquement acceptable possède un diamètre des particules volumique médian (d(0,5)) de 3 μm à 9 μm. La composition pharmaceutique de la présente invention présente les avantages d'une bonne stabilité, d'une vitesse de dissolution élevée, d'une uniformité améliorée du contenu et d'excellentes propriétés pharmacocinétiques. En raison de ces avantages, la composition pharmaceutique de la présente invention est efficace dans le traitement de l'inflammation ou de la douleur.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)