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1. (WO2015115507) HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/115507    International Application No.:    PCT/JP2015/052415
Publication Date: 06.08.2015 International Filing Date: 28.01.2015
IPC:
C07D 307/82 (2006.01), A61K 31/343 (2006.01), A61K 31/351 (2006.01), A61K 31/397 (2006.01), A61K 31/4025 (2006.01), A61K 31/422 (2006.01), A61K 31/427 (2006.01), A61K 31/4439 (2006.01), A61K 31/506 (2006.01), A61K 31/5377 (2006.01), A61K 31/5383 (2006.01), A61P 1/00 (2006.01), A61P 1/04 (2006.01), A61P 11/00 (2006.01), A61P 11/06 (2006.01), A61P 13/10 (2006.01), A61P 17/04 (2006.01), A61P 25/00 (2006.01), A61P 25/04 (2006.01), A61P 29/00 (2006.01), A61P 43/00 (2006.01), C07D 405/12 (2006.01), C07D 405/14 (2006.01), C07D 407/12 (2006.01), C07D 409/14 (2006.01), C07D 413/14 (2006.01), C07D 417/14 (2006.01), C07D 498/04 (2006.01)
Applicants: EA PHARMA CO., LTD. [JP/JP]; 2-1-1, Irifune, Chuo-ku, Tokyo 1040042 (JP)
Inventors: KOBAYASHI, Kaori; (JP).
SUZUKI, Tamotsu; (JP).
KAWAHIRA, Mizuki; (JP).
FUJII, Tomohiro; (JP).
SUGIKI, Masayuki; (JP).
OHSUMI, Koji; (JP).
OKUZUMI, Tatsuya; (JP)
Agent: TAKASHIMA, Hajime; (JP)
Priority Data:
2014-013729 28.01.2014 JP
2014-160250 06.08.2014 JP
Title (EN) HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME
(FR) DÉRIVÉ DE SULFONAMIDE HÉTÉROCYCLIQUE ET MÉDICAMENT LE CONTENANT
(JA) 複素環スルホンアミド誘導体及びそれを含有する医薬
Abstract: front page image
(EN)Provided is a compound represented by formula (I) [wherein each symbol is as defined in the description] or a pharmaceutically acceptable salt thereof. This compound has an excellent TRPA1 antagonistic activity, which makes it possible to provide a TRPA1 antagonist and a medicine that is useful for preventing or treating diseases associated with TRPA1.
(FR)L'invention porte sur un composé représenté par la formule (I) (dans laquelle chaque symbole est tel que défini dans la description) ou sur un sel pharmaceutiquement acceptable de celui-ci. Ce composé présente une excellente activité antagoniste vis-à-vis de la TRPA1, ce qui permet d'obtenir un antagoniste de la TRPA1 et un médicament qui est utile pour prévenir ou traiter des maladies associées à la TRPA1.
(JA) 本発明は、式(I): [式中、各記号は明細書中と同義である] で表される化合物またはその医薬上許容される塩を提供する。当該化合物は優れたTRPA1アンタゴニスト活性を有し、TRPA1アンタゴニスト及びTRPA1が関与する疾患の予防または治療に有用な薬剤の提供が可能となる。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)