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1. (WO2015114855) KINESIN INHIBITOR CONTAINING LUTEOLIN OR GLUCOSIDE THEREOF AS ACTIVE INGREDIENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2015/114855    International Application No.:    PCT/JP2014/068526
Publication Date: 06.08.2015 International Filing Date: 11.07.2014
IPC:
A61K 31/352 (2006.01), A23L 1/30 (2006.01), A23L 2/52 (2006.01), A61K 8/49 (2006.01), A61K 8/60 (2006.01), A61K 31/7048 (2006.01), A61P 17/00 (2006.01), A61P 43/00 (2006.01), A61Q 19/00 (2006.01), A61Q 19/02 (2006.01)
Applicants: ICHIMARU PHARCOS CO.,LTD. [JP/JP]; 318-1, Asagi, Motosu-shi, Gifu 5010475 (JP)
Inventors: TANAKA Kiyotaka; (JP).
KOJIMA Hiroyuki; (JP).
KAWAI Yuka; (JP)
Priority Data:
2014-013309 28.01.2014 JP
Title (EN) KINESIN INHIBITOR CONTAINING LUTEOLIN OR GLUCOSIDE THEREOF AS ACTIVE INGREDIENT
(FR) UTILISATION D'UN INHIBITEUR DE KINÉSINE CONTENANT DE LA LUTÉOLINE OU SON GLUCOSIDE COMME PRINCIPE ACTIF
(JA) ルテオリン又はその配糖体を有効成分とするキネシン抑制剤
Abstract: front page image
(EN)The purpose of the present invention is to provide: a novel and useful kinesin inhibitor; and a composition useful for the alleviation or prevention of various types of pigmentation symptoms including freckles and ephelides. Also provided is a kinesin inhibitor or a pigmentation preventing agent, each of which contains, as an active ingredient, a specific substance, i.e., luteolin or a glucoside thereof (e.g., luteolin-7-O-galactoside, luteolin-7-O-galactoside-4', luteolin-4'-O-glucuronide, luteolin-5-O-glucuronide, luteolin-7-O-glucuronide, luteolin-4'-O-glucoside, luteolin-7-O-glucoside). It also becomes possible to provide various compositions (i.e., a pharmaceutical composition, a food or beverage composition, a cosmetic composition) each containing a kinesin inhibitor or a pigmentation preventing agent.
(FR)L'invention concerne : un nouvel inhibiteur de kinésine utile ; et une composition utilisée pour atténuer ou prévenir différents types de symptômes de la pigmentation, notamment les éphélides ou taches de rousseur. L'invention concerne également un inhibiteur de kinésine ou un agent empêchant la pigmentation, chacun d'eux contenant, en tant que principe actif, une substance spécifique, c'est-à-dire la lutéoline ou son glucoside (par exemple les composés lutéoline-7-O-galactoside, lutéoline-7-O-galactoside-4', lutéoline-4'-O-glucuronide, lutéoline-5-O-glucuronide, lutéoline-7-O-glucuronide, lutéoline-4'-O-glucoside, lutéoline-7-O-glucoside). L'invention concerne également différentes compositions (composition pharmaceutique, composition alimentaire ou boisson, composition cosmétique) contenant chacune un inhibiteur de kinésine ou un agent empêchant la pigmentation.
(JA)新規で有用なキネシン抑制剤及び、シミやソバカスをはじめとする様々な色素沈着症状の緩和、抑制に有用な組成物を提供することである。また、特定の物質、ルテオリン又はその配糖体(ルテオリン-7-O-ガラクトシド、ルテオリン-7-O-ガラクトシド-4'、ルテオリン-4'-O-グルクロニド、ルテオリン-5-O-グルクロニド、ルテオリン-7-O-グルクロニド、ルテオリン-4'-O-グルコシド、ルテオリン-7-O-グルコシド)を有効成分として含有するキネシン抑制剤又は色素沈着抑制剤。更に、キネシン抑制剤又は色素沈着抑制剤を含有する各種組成物(医薬組成物、飲食品組成物、化粧料組成物)を提供することができる。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)